about
Modulation of the matrix redox signaling by mitochondrial Ca(2.)NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox stateOPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchangeAdvances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.L-OPA1 regulates mitoflash biogenesis independently from membrane fusion.A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells.Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells.Antibiotics induce mitonuclear protein imbalance but fail to inhibit respiration and nutrient activation in pancreatic β-cells.Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cellsMitochondrial ion channels in pancreatic β-cells: Novel pharmacological targets for the treatment of Type 2 diabetesRegulation of inositol 1,4,5-trisphosphate-induced Ca2+ release from the endoplasmic reticulum by AMP-activated kinase modulatorsProtein Lysine Acetylation: Grease or Sand in the Gears of β-Cell Mitochondria?The plant product quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic beta cellsCellular stress is a prerequisite for glucose-induced mitochondrial matrix alkalinization in pancreatic β-cells
P50
Q26775419-8295D17D-CC1C-428F-9FBA-40685B7D403AQ30274645-C8DB56ED-41D3-4D21-9F9A-78B15334AB26Q30575770-7DDD117D-F68E-46B5-AE23-4F3DF9D588E4Q30845005-331435B7-5D83-488D-85B2-52CF448FD679Q37672750-E434594E-FB2B-4ED3-B620-13F01A0A951FQ38707917-13C7FC99-AB74-45C7-852A-698C19818646Q38727239-05B92AAB-F7F9-4294-83D6-E83EE66B7FCAQ47885717-FFD4CAD0-74E7-494C-A351-7E3F1702CFA5Q64260502-9F4A25C4-493B-4D02-8956-FE8E8C6BBAABQ89706884-9149D677-9311-411E-B805-739369EC8E04Q90587335-FC23593D-B54E-490C-8BF4-FC18697C5226Q90817070-859316B4-A1F7-4096-8C90-C904083037F3Q92534167-79719AF6-1105-4DF3-B136-A2ED736D475DQ93373418-F9763CB0-5A12-4041-88BE-66412B6552BA
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Jaime Santo-Domingo
@en
Jaime Santo-Domingo
@nl
type
label
Jaime Santo-Domingo
@en
Jaime Santo-Domingo
@nl
prefLabel
Jaime Santo-Domingo
@en
Jaime Santo-Domingo
@nl
P31
P496
0000-0001-5501-0482