about
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical painMultiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1.Conopeptide-Derived κ-Opioid Agonists (Conorphins): Potent, Selective, and Metabolic Stable Dynorphin A Mimetics with Antinociceptive Properties.Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif.α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways.Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.Voltage-gated sodium channels: (NaV )igating the field to determine their contribution to visceral nociception.CO-EXPRESSION OF μ AND ∂ OPIOID RECEPTORS BY MOUSE COLONIC NOCICEPTORS.Contribution of membrane receptor signalling to chronic visceral pain.Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunctionSelenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal painStructure–Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndromeNaV1.1 inhibition can reduce visceral hypersensitivityActivation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivityTranslating peripheral bladder afferent mechanosensitivity to neuronal activation within the lumbosacral spinal cord of miceHistamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1NaV 1.6 regulates excitability of mechanosensitive sensory neuronsLinaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talkColonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord
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P50
description
investigador
@es
researcher
@en
name
Joel Castro
@en
type
label
Joel Castro
@en
prefLabel
Joel Castro
@en
P31
P496
0000-0002-5781-2224