about
An affinity-directed protein missile system for targeted proteolysis.Targeting endogenous proteins for degradation through the affinity-directed protein missile system.PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition.The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.PAWS1 controls Wnt signalling through association with casein kinase 1α.Mitotic kinase anchoring proteins: the navigators of cell divisionPathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signallingAdvances in targeted degradation of endogenous proteinsFAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioningSalt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses
P50
Q41643543-D5AB84B8-6227-45DC-9079-6C7FFDE1F9B3Q42234304-3097B12E-2EEB-4F6E-B07E-16DD2426F446Q47364356-466406F1-D01E-4031-8BFF-5E270ADB02F6Q48152733-3877BE40-5B07-47AC-83C2-BC15075F11C5Q54978506-9DBA6386-6D11-4387-9E62-12665A65F6DEQ54982388-6B5B94AD-0D14-4C99-8B7A-F78908A71BA3Q89673525-3ACF9901-92D3-492A-BA9C-D38FFBA0E481Q90964326-505F2E3D-2199-4FA7-91A5-82103D40D53DQ91571220-88963597-6F3D-4A5A-A8DB-8C9978FDEF1EQ92141695-FF2D0CB3-E31C-4439-8A19-5DD7ADD712E6Q92859971-F437EDFE-0F02-4E12-859D-5F66D86D49FC
P50
description
researcher
@en
wetenschapper
@nl
name
Gopal P Sapkota
@en
Gopal P Sapkota
@nl
type
label
Gopal P Sapkota
@en
Gopal P Sapkota
@nl
prefLabel
Gopal P Sapkota
@en
Gopal P Sapkota
@nl
P31
P496
0000-0001-9931-3338