about
VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damageVRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?Olaparib and ionizing radiation trigger a cooperative DNA-damage repair response that is impaired by depletion of the VRK1 chromatin kinase
P50
description
researcher
@en
name
Ignacio Campillo-Marcos
@en
type
label
Ignacio Campillo-Marcos
@en
prefLabel
Ignacio Campillo-Marcos
@en
P31
P496
0000-0002-7657-7127