about
Acquired resistance of phosphatase and tensin homolog-deficient cells to poly(ADP-ribose) polymerase inhibitor and Ara-C mediated by 53BP1 loss and SAMHD1 overexpression.Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicityInhibition of the BET family reduces its new target gene IDO1 expression and the production of L-kynurenine
P50
description
researcher
@en
name
Hua-Dong Chen
@en
type
label
Hua-Dong Chen
@en
prefLabel
Hua-Dong Chen
@en
P31
P496
0000-0003-4681-0853