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HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunityHistone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodelingThe SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonistsHDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonistsA molecular switch regulating transcriptional repression and activation of PPARγQuantitative structural assessment of graded receptor agonismStructural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug PioglitazoneDefinition of functionally and structurally distinct repressive states in the nuclear receptor PPARγUnique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways
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P50
description
researcher
@en
wetenschapper
@nl
name
Patrick R Griffin
@en
Patrick R Griffin
@nl
type
label
Patrick R Griffin
@en
Patrick R Griffin
@nl
prefLabel
Patrick R Griffin
@en
Patrick R Griffin
@nl
P108
P31
P496
0000-0002-3404-690X