about
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signalingUNC93B1 mediates host resistance to infection with Toxoplasma gondiiLipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transductionToll-like receptorsThe Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomesTLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant ratNLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsSerum cytokine profiles associated with specific adjuvants used in a DNA prime-protein boost vaccination strategy.RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages.Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motifMD-2-mediated ionic interactions between lipid A and TLR4 are essential for receptor activation.Differential gene expression downstream of Toll-like receptors (TLRs): role of c-Src and activating transcription factor 3 (ATF3).Human C4b-binding protein selectively interacts with Neisseria gonorrhoeae and results in species-specific infection.Toll-like receptor 2 deficiency results in impaired antibody responses and septic shock during Borrelia hermsii infection.A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.Toll-like receptors and their function in innate and adaptive immunity.Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36.Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.Evaluation of the role of LcrV-Toll-like receptor 2-mediated immunomodulation in the virulence of Yersinia pestis.The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants.Phagocytosis and intracellular killing of MD-2 opsonized gram-negative bacteria depend on TLR4 signaling.Manipulation of Interleukin-1β and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence.Reduced MyD88 dependency of ISCOMATRIX™ adjuvant in a DNA prime-protein boost HIV vaccine.Yersinia pestis evades TLR4-dependent induction of IL-12(p40)2 by dendritic cells and subsequent cell migrationRole of p38 and early growth response factor 1 in the macrophage response to group B streptococcus.D27-pLpxL, an avirulent strain of Yersinia pestis, primes T cells that protect against pneumonic plague.The role of Toll-like receptor pathways in the mechanism of type 1 diabetes.Inflammasomes and host defenses against bacterial infections.Mammalian Lipopolysaccharide Receptors Incorporated into the Retroviral Envelope Augment Virus Transmission.Defects in early cell recruitment contribute to the increased susceptibility to respiratory Klebsiella pneumoniae infection in diabetic mice.(De-) oiling inflammasomes.Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling.Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi.MD-2 expression is not required for cell surface targeting of Toll-like receptor 4 (TLR4).Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever.Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.The LPS receptor generates inflammatory signals from the cell surface.
P50
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P50
description
researcher (ORCID 0000-0002-8536-2419)
@en
wetenschapper
@nl
name
Egil Lien
@en
Egil Lien
@nl
type
label
Egil Lien
@en
Egil Lien
@nl
prefLabel
Egil Lien
@en
Egil Lien
@nl
P106
P21
P31
P496
0000-0002-8536-2419