about
Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding.c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun.Arrestin-3-Dependent Activation of c-Jun N-Terminal Kinases (JNKs).Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth.Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2.Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations.Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanomaArrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplificationModulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivoQuantification of ERK Kinase Activity in Biological Samples Using Differential SensingNO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growthA Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate PhosphorylationJNK2 Is Required for the Tumorigenic Properties of Melanoma CellsArrestin-3 interaction with maternal embryonic leucine-zipper kinaseDesign, synthesis, and DNA interaction studies of furo-imidazo[3.3.3]propellane derivatives: Potential anticancer agents
P50
Q37415694-ABDA978F-7302-4D6C-9C3C-6A6D152FE8FAQ39110390-7B7CEB60-523E-4DC1-A030-3855DA5D9334Q41833000-76FC1B38-F1CA-40F1-843A-292EB3F46D22Q47619144-211136D5-47AD-47C2-BC6C-C8193944162FQ48112839-17935B88-7AF2-47DC-9627-9D03C6EA339EQ50069882-14DCAA3A-BD60-4B69-A5DA-9090180C2B55Q58570579-3CF8E8FA-762F-44FF-89BA-FABE76966EFDQ90784815-3FA91855-8E42-4C15-BCDD-0FAF8D34D07CQ91344488-E4D62FAE-5DBD-46A7-AF0B-D0B19AFF9C69Q91489417-2D8E6817-9F16-4A69-AE15-35973F3E5771Q91556032-C081F3C3-40CF-4E8D-BFCF-A8A194EA1E39Q91781419-A940E6AA-0B8E-433D-BE83-AA0A6B9C3143Q91820582-53891F17-AF0D-43B2-B3FD-5A30DEAAFDA1Q92224206-E7694F8B-BE1C-4FCF-BB8B-B7EA7E621169Q92414030-04802BC8-5C6E-4790-BE92-A70E9AB7CCC9
P50
description
researcher (ORCID 0000-0003-1298-8725)
@en
name
Tamer S Kaoud
@en
type
label
Tamer S Kaoud
@en
prefLabel
Tamer S Kaoud
@en
P31
P496
0000-0003-1298-8725