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Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapyThe LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback LoopAutomethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteinsFunctional Genomics, Genetics, and Bioinformatics 2016PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agentsCritical roles of non-histone protein lysine methylation in human tumorigenesis.SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.Critical roles of SMYD2-mediated β-catenin methylation for nuclear translocation and activation of Wnt signaling.
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description
wetenschapper
@nl
name
Ryuji Hamamoto
@en
Ryuji Hamamoto
@nl
type
label
Ryuji Hamamoto
@en
Ryuji Hamamoto
@nl
prefLabel
Ryuji Hamamoto
@en
Ryuji Hamamoto
@nl
P31
P496
0000-0002-2632-1334