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Q24647774-5B6D5ACA-EE12-4365-BD5E-D01AF2502E22
Q24647774-5B6D5ACA-EE12-4365-BD5E-D01AF2502E22
BestRank
Statement
http://www.wikidata.org/entity/statement/Q24647774-5B6D5ACA-EE12-4365-BD5E-D01AF2502E22
IRS1-independent defects define major nodes of insulin resistance
P2860
Q24647774-5B6D5ACA-EE12-4365-BD5E-D01AF2502E22
BestRank
Statement
http://www.wikidata.org/entity/statement/Q24647774-5B6D5ACA-EE12-4365-BD5E-D01AF2502E22
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wasDerivedFrom
6dccaa3180a341166163aa9877f6df4bbeb0bbda
P2860
A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory