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Q27024233-BC6D7D55-55C9-4F5E-BDE2-911397129A49
Q27024233-BC6D7D55-55C9-4F5E-BDE2-911397129A49
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Statement
http://www.wikidata.org/entity/statement/Q27024233-BC6D7D55-55C9-4F5E-BDE2-911397129A49
Gain-of-function mutation of chromatin regulators as a tumorigenic mechanism and an opportunity for therapeutic intervention
P2860
Q27024233-BC6D7D55-55C9-4F5E-BDE2-911397129A49
BestRank
Statement
http://www.wikidata.org/entity/statement/Q27024233-BC6D7D55-55C9-4F5E-BDE2-911397129A49
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wasDerivedFrom
76156d48208d4d32d97796def431e7162ef388e0
P2860
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.