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Q35114397-0ADBE410-F386-482E-80B4-21A7CEFC1F8E
Q35114397-0ADBE410-F386-482E-80B4-21A7CEFC1F8E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35114397-0ADBE410-F386-482E-80B4-21A7CEFC1F8E
Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia.
P2860
Q35114397-0ADBE410-F386-482E-80B4-21A7CEFC1F8E
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35114397-0ADBE410-F386-482E-80B4-21A7CEFC1F8E
rank
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wasDerivedFrom
3088d6a3a2bdc8466c932a8553e53ec3dab80868
P2860
Transformation by oncogenic mutants and ligand-dependent activation of FLT3 wild-type requires the tyrosine residues 589 and 591.