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Q36751725-2E231EE6-3616-4F65-9797-E11BFDE5CFD1
Q36751725-2E231EE6-3616-4F65-9797-E11BFDE5CFD1
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Statement
http://www.wikidata.org/entity/statement/Q36751725-2E231EE6-3616-4F65-9797-E11BFDE5CFD1
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death.
P2860
Q36751725-2E231EE6-3616-4F65-9797-E11BFDE5CFD1
BestRank
Statement
http://www.wikidata.org/entity/statement/Q36751725-2E231EE6-3616-4F65-9797-E11BFDE5CFD1
rank
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type
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Statement
wasDerivedFrom
0ff440c56b6db4f94a38e98eeaa00b71475d4794
P2860
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone