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Q38724344-B0CD620D-1B50-42D1-95EA-67F2D4ABAFF6
Q38724344-B0CD620D-1B50-42D1-95EA-67F2D4ABAFF6
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http://www.wikidata.org/entity/statement/Q38724344-B0CD620D-1B50-42D1-95EA-67F2D4ABAFF6
Mutations in NOTCH1 PEST-domain orchestrate CCL19-driven homing of Chronic Lymphocytic Leukemia cells by modulating the tumor suppressor gene DUSP22.
P2860
Q38724344-B0CD620D-1B50-42D1-95EA-67F2D4ABAFF6
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38724344-B0CD620D-1B50-42D1-95EA-67F2D4ABAFF6
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wasDerivedFrom
ba739a82c818d476df070f65c01264f2a563b373
P2860
Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism.