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Q39699169-E2AF4E54-F928-49A8-8211-52E637EF4B79
Q39699169-E2AF4E54-F928-49A8-8211-52E637EF4B79
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39699169-E2AF4E54-F928-49A8-8211-52E637EF4B79
The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1.
P2860
Q39699169-E2AF4E54-F928-49A8-8211-52E637EF4B79
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39699169-E2AF4E54-F928-49A8-8211-52E637EF4B79
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wasDerivedFrom
2c4310f1d38763d05314ce394db07c8aa25c2c0f
P2860
Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth.