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Q47220295-E39132BD-A1C3-4489-A4ED-4F7E4D7CCF92
Q47220295-E39132BD-A1C3-4489-A4ED-4F7E4D7CCF92
BestRank
Statement
http://www.wikidata.org/entity/statement/Q47220295-E39132BD-A1C3-4489-A4ED-4F7E4D7CCF92
Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?
P2860
Q47220295-E39132BD-A1C3-4489-A4ED-4F7E4D7CCF92
BestRank
Statement
http://www.wikidata.org/entity/statement/Q47220295-E39132BD-A1C3-4489-A4ED-4F7E4D7CCF92
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type
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Statement
wasDerivedFrom
9709a815db72701e56e805a80677532bd0b07fba
P2860
An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.