Objective response rate according to RECIST 1.1 Up to 1 year [clinicaltrials_resource:397acc363d9d09b41ecd9e77b31b1626]

90% exact confidence interval will be constructed for the overall group and for all the marker subgroups respectively. Fisher's exact test will be applied to test the equal response rates between the two groups with a one-sided 5% type I error rate.

Objective response rate according to RECIST 1.1 Up to 1 year [clinicaltrials_resource:397acc363d9d09b41ecd9e77b31b1626]

90% exact confidence interval will be constructed for the overall group and for all the marker subgroups respectively. Fisher's exact test will be applied to test the equal response rates between the two groups with a one-sided 5% type I error rate.