Maximum Tolerated Dose (MTD) Cycle 1 (within the first 4 weeks) [clinicaltrials_resource:4a57afd6bcc239220dc4fd4349fdffb4]

Administered intravenously once weekly for 4 weeks (1 cycle). In the absence of disease progression or unacceptable toxicity, patients could continue to receive additional cycles.

Maximum Tolerated Dose (MTD) Cycle 1 (within the first 4 weeks) [clinicaltrials_resource:4a57afd6bcc239220dc4fd4349fdffb4]

Administered intravenously once weekly for 4 weeks (1 cycle). In the absence of disease progression or unacceptable toxicity, patients could continue to receive additional cycles.