To determine the maximum tolerated dose (MTD) and dose limiting toxicity (DLT) of INNO-406 when administered as a single agent to adult patients with imatinib-resistant or intolerant Ph+ leukemias. One year [clinicaltrials_resource:53de3a681a0ded64457a311c4f638bc0]

Oral, twice daily self-administration of 10 mg and/or 50 mg tablets

To determine the maximum tolerated dose (MTD) and dose limiting toxicity (DLT) of INNO-406 when administered as a single agent to adult patients with imatinib-resistant or intolerant Ph+ leukemias. One year [clinicaltrials_resource:53de3a681a0ded64457a311c4f638bc0]

Oral, twice daily self-administration of 10 mg and/or 50 mg tablets