To determine whether addition of neoadjuvant chemotherapy before definite CCRT increase progression-free survival(PFS) compared with CCRT only 18 months after the enrollment of the last patients [clinicaltrials_resource:5c49a4d4df7ab0fd22d0474dd516c34c]

no neoadjuvant chemotherapy before definitive CCRT

To determine whether addition of neoadjuvant chemotherapy before definite CCRT increase progression-free survival(PFS) compared with CCRT only 18 months after the enrollment of the last patients [clinicaltrials_resource:5c49a4d4df7ab0fd22d0474dd516c34c]

no neoadjuvant chemotherapy before definitive CCRT