Retinal nerve fibre layer At baseline and every three months for nine months [clinicaltrials_resource:62d276c14bc8e4ff81db7a14b37ce5df]

The primary aim of this open-label pilot trial is to estimate the treatment effect of 100 mg of oral minocycline twice daily for 90 days, initiated within 30 days of onset of ON, on functional and structural optic nerve recovery compared to no treatment. The primary outcome measure that will be used to measure optic nerve recovery is RNFL thickness.

Retinal nerve fibre layer At baseline and every three months for nine months [clinicaltrials_resource:62d276c14bc8e4ff81db7a14b37ce5df]

The primary aim of this open-label pilot trial is to estimate the treatment effect of 100 mg of oral minocycline twice daily for 90 days, initiated within 30 days of onset of ON, on functional and structural optic nerve recovery compared to no treatment. The primary outcome measure that will be used to measure optic nerve recovery is RNFL thickness.