Change From Baseline in Annual Rate of Growth Standard Deviation Score (SDS) at Year 3 Baseline, Year 3 [clinicaltrials_resource:6fbc2b47305ea1e0c879e8b23cf35acb]

Annual rate of growth SDS was obtained by measuring the annual growth rate, subtracting chronological age- and gender-appropriate mean annual growth rate and dividing the result by standard deviation of that mean (as obtained from chronological age- and gender-specific population reference data). SDS indicated how many standard deviations higher (in case of positive SDS) or lower (in case of negative SDS) participant's value was relative to the mean of the reference population.

Change From Baseline in Annual Rate of Growth Standard Deviation Score (SDS) at Year 3 Baseline, Year 3 [clinicaltrials_resource:6fbc2b47305ea1e0c879e8b23cf35acb]

Annual rate of growth SDS was obtained by measuring the annual growth rate, subtracting chronological age- and gender-appropriate mean annual growth rate and dividing the result by standard deviation of that mean (as obtained from chronological age- and gender-specific population reference data). SDS indicated how many standard deviations higher (in case of positive SDS) or lower (in case of negative SDS) participant's value was relative to the mean of the reference population.