The Maximum Tolerated Dose (MTD) of Oral Clofarabine in Adult Patients With Relapsed CD20+ Non-Hodgkin Lymphoma(NHL) 14 days for up to 8 cycles (1 cycle equals 14 days on drug, 14 days off drug) for a total of up to 224 days [clinicaltrials_resource:784f522f535fd1e2d8d60625a9c7dce4]
Initially, 3 patients will be enrolled into a dose level during the dose-escalation portion:
If no patient experiences dose-limiting toxicities during the first 4 weeks, then 3 patients will be enrolled into the next dose level.
If one of the three patients develops dose-limiting toxicities, then 3 additional patients will be enrolled in that cohort. If none of the additional 3 patients experiences dose-limiting toxicities, then further dose-escalation occurs.
If one additional patient experiences dose-limiting toxicities, then the maximum tolerated dose is exceeded.
clinicaltrials_vocabulary:secondary outcome [clinicaltrials_vocabulary:clinicaltrials_vocabulary:secondary-outcome]
The Maximum Tolerated Dose (MTD) of Oral Clofarabine in Adult Patients With Relapsed CD20+ Non-Hodgkin Lymphoma(NHL) 14 days for up to 8 cycles (1 cycle equals 14 days on drug, 14 days off drug) for a total of up to 224 days [clinicaltrials_resource:784f522f535fd1e2d8d60625a9c7dce4]
Initially, 3 patients will be enrolled into a dose level during the dose-escalation portion:
If no patient experiences dose-limiting toxicities during the first 4 weeks, then 3 patients will be enrolled into the next dose level.
If one of the three patients develops dose-limiting toxicities, then 3 additional patients will be enrolled in that cohort. If none of the additional 3 patients experiences dose-limiting toxicities, then further dose-escalation occurs.
If one additional patient experiences dose-limiting toxicities, then the maximum tolerated dose is exceeded.
Bio2RDF identifier
784f522f535fd1e2d8d60625a9c7dce4
Bio2RDF namespace
clinicaltrials_resource
Bio2RDF uri
http://bio2rdf.org/clinicaltrials_resource:784f522f535fd1e2d8d60625a9c7dce4
measure [clinicaltrials_vocabulary:measure]
The Maximum Tolerated Dose (MT ...... D20+ Non-Hodgkin Lymphoma(NHL)
time frame [clinicaltrials_vocabulary:time-frame]
14 days for up to 8 cycles (1 ...... for a total of up to 224 days
description
Initially, 3 patients will be ...... um tolerated dose is exceeded.
identifier
clinicaltrials_resource:784f522f535fd1e2d8d60625a9c7dce4
title
The Maximum Tolerated Dose (MT ...... for a total of up to 224 days
@en
type
label
The Maximum Tolerated Dose (MT ...... f522f535fd1e2d8d60625a9c7dce4]
@en