Adverse events, serious adverse events, assessments of clinical laboratory values, and vital sign measurements 12 months [clinicaltrials_resource:9649f9cb90cad62ccbcbb596a8f90678]

MLN4924 intravenous (IV) on a 21-day cycle on one of the following schedules: Days 1, 3, and 5, followed by a rest period of 16 days (Schedule A) Days 1, 4, 8, and 11, followed by a rest period of 10 days (Schedule B) Continuous weekly dosing on Days 1, 8, and 15 (Schedule C) Days 1, 4, 11, 15 for Cycle 1 only; Days 1, 4, 8, 11 for all subsequent cycles (Schedule D) Dosing on Days 1, 3, and 5 in patients with high-grade MDS or AML (Schedule E)

Adverse events, serious adverse events, assessments of clinical laboratory values, and vital sign measurements 12 months [clinicaltrials_resource:9649f9cb90cad62ccbcbb596a8f90678]

MLN4924 intravenous (IV) on a 21-day cycle on one of the following schedules: Days 1, 3, and 5, followed by a rest period of 16 days (Schedule A) Days 1, 4, 8, and 11, followed by a rest period of 10 days (Schedule B) Continuous weekly dosing on Days 1, 8, and 15 (Schedule C) Days 1, 4, 11, 15 for Cycle 1 only; Days 1, 4, 8, 11 for all subsequent cycles (Schedule D) Dosing on Days 1, 3, and 5 in patients with high-grade MDS or AML (Schedule E)