Ventilator-associated pneumonia Subjects will be assessed for this outcome from the date of randomization until discharge from the ICU (up to 30 days post-randomization) [clinicaltrials_resource:bcbb10aa4e53ab5c29020bc659a9d8cc]

Oral hygiene provided by current local standard of care - minimum q2h mouthcare with a green Toothette swab dipped in sterile water, with excess liquid aspirated using a Yankauer suction. Brushing of teeth (if applicable) with a toothbrush and standard toothpaste q12h. Replacement of Yankauer suction device daily.

Ventilator-associated pneumonia Subjects will be assessed for this outcome from the date of randomization until discharge from the ICU (up to 30 days post-randomization) [clinicaltrials_resource:bcbb10aa4e53ab5c29020bc659a9d8cc]

Oral hygiene provided by current local standard of care - minimum q2h mouthcare with a green Toothette swab dipped in sterile water, with excess liquid aspirated using a Yankauer suction. Brushing of teeth (if applicable) with a toothbrush and standard toothpaste q12h. Replacement of Yankauer suction device daily.