Pharmacokinetic (PK) exposure parameters of lumefantrine 28 days [clinicaltrials_resource:d273815f150b7afee9139ff7532b8f1e]
Sparse pharmacokinetic data will be pooled for evaluation of both individual and population PK parameter estimates of lumefantrine using Non linear mixed effect model. Pharmacokinetic exposure will be depicted principally by area under the concentration-time curves following the last dose through to 28 days of follow up (AUC0-28). Other PK parameters portraying exposure will also be assessed alongside. These include half life (t1/2), peak concentrations (Cmax) and time to reach Cmax (Tmax), apparent clearance and volumes of distribution.
clinicaltrials_vocabulary:other outcome [clinicaltrials_vocabulary:clinicaltrials_vocabulary:other-outcome]
Pharmacokinetic (PK) exposure parameters of lumefantrine 28 days [clinicaltrials_resource:d273815f150b7afee9139ff7532b8f1e]
Sparse pharmacokinetic data will be pooled for evaluation of both individual and population PK parameter estimates of lumefantrine using Non linear mixed effect model. Pharmacokinetic exposure will be depicted principally by area under the concentration-time curves following the last dose through to 28 days of follow up (AUC0-28). Other PK parameters portraying exposure will also be assessed alongside. These include half life (t1/2), peak concentrations (Cmax) and time to reach Cmax (Tmax), apparent clearance and volumes of distribution.
Bio2RDF identifier
d273815f150b7afee9139ff7532b8f1e
Bio2RDF namespace
clinicaltrials_resource
Bio2RDF uri
http://bio2rdf.org/clinicaltrials_resource:d273815f150b7afee9139ff7532b8f1e
measure [clinicaltrials_vocabulary:measure]
Pharmacokinetic (PK) exposure parameters of lumefantrine
time frame [clinicaltrials_vocabulary:time-frame]
description
Sparse pharmacokinetic data wi ...... e and volumes of distribution.
identifier
clinicaltrials_resource:d273815f150b7afee9139ff7532b8f1e
title
Pharmacokinetic (PK) exposure parameters of lumefantrine 28 days
@en
type
label
Pharmacokinetic (PK) exposure ...... 3815f150b7afee9139ff7532b8f1e]
@en