Depth of sedation using the RASS. The target RASS range (target depth of sedation) should be 0 to -3 for a patient to be included in the study. The target may be amended during the study treatment, if clinically required RASS score will be assessed approximately 2 hourly during the treatment period and during the 48-hour follow-up period [clinicaltrials_resource:f03a2f8152c48c6b0410df4aad9586f4]

Dexmedetomidine

Depth of sedation using the RASS. The target RASS range (target depth of sedation) should be 0 to -3 for a patient to be included in the study. The target may be amended during the study treatment, if clinically required RASS score will be assessed approximately 2 hourly during the treatment period and during the 48-hour follow-up period [clinicaltrials_resource:f03a2f8152c48c6b0410df4aad9586f4]

Dexmedetomidine