Pharmacokinetic (PK) exposure parameters of lumefantrine 28 days [clinicaltrials_resource:fd6198808df873ca49c2f06888419da8]
Sparse pharmacokinetic data will be pooled for evaluation of both individual and population PK parameter estimates of lumefantrine using Non linear mixed effect model. Pharmacokinetic exposure will be depicted principally by area under the concentration-time curves following the last dose through to 28 days of follow up (AUC0-28). Other PK parameters portraying exposure will also be assessed alongside. These include half life (t1/2), peak concentrations (Cmax) and time to reach Cmax (Tmax), apparent clearance and volumes of distribution.
clinicaltrials_vocabulary:primary outcome [clinicaltrials_vocabulary:clinicaltrials_vocabulary:primary-outcome]
Pharmacokinetic (PK) exposure parameters of lumefantrine 28 days [clinicaltrials_resource:fd6198808df873ca49c2f06888419da8]
Sparse pharmacokinetic data will be pooled for evaluation of both individual and population PK parameter estimates of lumefantrine using Non linear mixed effect model. Pharmacokinetic exposure will be depicted principally by area under the concentration-time curves following the last dose through to 28 days of follow up (AUC0-28). Other PK parameters portraying exposure will also be assessed alongside. These include half life (t1/2), peak concentrations (Cmax) and time to reach Cmax (Tmax), apparent clearance and volumes of distribution.
Bio2RDF identifier
fd6198808df873ca49c2f06888419da8
Bio2RDF namespace
clinicaltrials_resource
Bio2RDF uri
http://bio2rdf.org/clinicaltrials_resource:fd6198808df873ca49c2f06888419da8
measure [clinicaltrials_vocabulary:measure]
Pharmacokinetic (PK) exposure parameters of lumefantrine
time frame [clinicaltrials_vocabulary:time-frame]
description
Sparse pharmacokinetic data wi ...... e and volumes of distribution.
identifier
clinicaltrials_resource:fd6198808df873ca49c2f06888419da8
title
Pharmacokinetic (PK) exposure parameters of lumefantrine 28 days
@en
type
label
Pharmacokinetic (PK) exposure ...... 198808df873ca49c2f06888419da8]
@en