about
CalreticulinTransformation related protein 53Breast cancer 1, early onsetB cell leukemia/lymphoma 2Ubiquitin carboxy-terminal hydrolase L1Parkin RBR E3 ubiquitin protein ligaseMyogenic differentiation 1Heat shock protein 1 (chaperonin)Glucose-6-phosphate isomerase 1VinculinChemokine (C-X-C motif) receptor 4Erb-b2 receptor tyrosine kinase 2Heat shock protein 8Cyclin-dependent kinase inhibitor 1A (P21)SMAD family member 2SMAD family member 3SMAD family member 6SMAD family member 6SMAD family member 5SMAD family member 5SMAD family member 7Sodium channel, voltage-gated, type V, alphaAurora kinase APaxillinSpleen tyrosine kinaseFas death domain-associated proteinInhibitor of kappaB kinase gammaTransforming growth factor, beta receptor IJun proto-oncogeneCaspase 8Checkpoint kinase 2FMS-like tyrosine kinase 3Cystathionine beta-synthaseSKI proto-oncogenePotassium voltage-gated channel, subfamily Q, member 3TNF receptor-associated factor 2Lymphotoxin B receptorPaired box 6Activin A receptor type 1BPeriod circadian clock 3
P680
Identification of the receptor component of the IkappaBalpha-ubiquitin ligaseThe human RAD18 gene product interacts with HHR6A and HHR6BRBP95, a novel leucine zipper protein, binds to the retinoblastoma proteinInteraction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymesFeatures of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of ParkinTEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulumSpongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal traffickingStructural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradationThe interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaBRNF34 is a cold-regulated E3 ubiquitin ligase for PGC-1α and modulates brown fat cell metabolismParkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formationCritical role for Daxx in regulating Mdm2Control of PKA stability and signalling by the RING ligase praja2The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutationsUBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signallingUBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulationUBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybridsParkin mono-ubiquitinates Bcl-2 and regulates autophagyCHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activityPHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencingArkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signalingThe E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of TaraSolubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminaseEGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradationThe EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCIProteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial functionParkin interacts with Ambra1 to induce mitophagyRecognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forksMahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with GalphasTripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domainStructure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domainCARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressorRegulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)
P921
Q14633944-76905EA7-7FC4-4DB6-AFFB-3F0720B8BE02Q14818136-33AF8580-9F72-45EE-9AAD-EB4B3D73D1FFQ14818136-74DFBD3B-1526-4000-9A14-2428619C44B3Q14818136-90DBB6A5-852B-4656-A4AC-389F77DA944AQ14862232-32D77967-371A-47A8-9580-8DECCBAA7E34Q14863583-CDC11FE3-10F4-4F70-ABE7-C2730D933A90Q14864242-22616CCC-50B5-4D8F-8E82-54DB4DE54D9BQ14864264-82C944D8-10DB-4F61-B612-16BAA507D8F8Q14864495-705BA8FA-1D4A-47C0-A927-142EC8AE7703Q14865001-51B317E0-885D-4402-8034-A63B476680F2Q14865001-A700B57B-B85C-4225-9F2C-6333D9B390E6Q14865772-2E486C51-3209-4E78-8E26-F37C558BCFBFQ14865772-A763ED24-DFCD-4D80-ABCE-0AF83A5C7822Q14873347-8E3ED21A-65A6-46A3-89DA-BD0FE36D9552Q14874287-EC83B9D8-8A54-472B-A33C-6E04878706CDQ14877504-DAFB21AD-E4A1-4093-8591-C58D20CFD567Q14888957-2FE559B3-F047-425F-BE66-041FEE216D81Q14888957-C5F9650D-9101-4F3A-BAE0-60C50DACF3DDQ14902457-D36324D5-325F-4883-B7E8-CA88B4FAAC98Q14903951-CAB0B4FB-F660-4BC7-A65A-51627A49D52FQ14903978-FBD0A627-6787-4F67-84C3-1B1E2FF517DBQ14904318-B98500C6-A009-4B39-84FA-3EE9C91343F9Q14904341-B829104D-255C-45A7-9414-22B97DE88F31Q14904349-145F0E24-7AA1-4388-9840-7211E2B748BAQ14904355-CA192EB9-DA73-4A9E-A168-3377DE939B4DQ14904377-B653D7A6-CD47-4F89-AFF0-AA834059D52DQ14905733-DA0B3275-4408-4AF3-9EEB-AC98E3978E65Q14906052-081E0AD3-456A-433C-801E-5929AFF27A21Q14906595-6B8B880A-1AF3-4C5C-9B80-2E3BF28626D6Q14907340-909DAD5D-DDEA-4BD5-A31E-D8FF6C02F377Q14908180-FC68BFD9-3B2B-4637-9CBD-358D2D5FA709Q14908211-F006A4D0-332F-4345-B80D-7C570C094A5CQ14911575-3E960A8E-4110-4843-963F-089591681993Q14911910-74EBFA4C-4E02-4C60-8738-0B83489F09F6Q14911968-952CB8FC-0C43-4834-890B-788AE45F832AQ14912285-BC8B81C0-A733-4B8D-BCAE-FD50F4C27E39Q14912405-D9D5766F-3759-4E37-92DB-B958D37FC11EQ14913099-B113F1D5-8B16-4510-BED9-942219385A22Q14913250-8715A81E-6628-4BB7-B0F2-6A3A290CE14FQ14914320-C441520D-C2E1-407E-B675-35DC036B20F2
P680
Q22008569-B7FDAE9A-AA5E-463B-8181-6CE2FFE2BCB3Q22254654-D8BE3C64-ADD2-4BF0-9B19-9964624AA8CFQ24289568-575BE49F-11DC-4CE8-928D-E4823CBE0979Q24290986-70A4ED95-2BB6-4125-A6E6-A970D8BF0C67Q24291032-1A5FC98C-97F7-4350-8281-7A8616B5538CQ24291412-C7D1C4FA-E78C-41E1-923A-8E8B072C4F43Q24292812-4A4D6873-362B-41D2-BAE6-73EAF8A53521Q24293322-F15CF6FC-4D96-48A1-9D18-9B9F1025FAFAQ24293794-F2AC6704-0BE1-4598-ABF1-01C11682158EQ24294762-2B702E8B-6810-4D88-BE61-CF080B220A6DQ24295552-5FE8F056-8B90-4F6D-BBDE-1B74372249DEQ24296350-94539F51-2FD6-4302-B731-0EF0F3D1EF34Q24296620-73CD5E30-19BC-41D6-AF4E-40B0EA1D6815Q24297332-E06A2517-C08A-468C-890C-708625A757FDQ24297791-9E73EF70-BD55-4CC4-99EB-1FFF4F2909D5Q24297798-5FDD64FE-44C2-46D4-A33F-1EE5E935BDF7Q24297826-84EA7839-2168-4AEE-8A6E-AC996B0AD1C8Q24299327-D3AFFBCA-0E1F-4A0A-9738-793903EF670AQ24300065-39B6A47B-7AAC-4FFE-873F-CF26E06439E3Q24300880-7B3DB928-A689-40E2-95A3-84ED7F4A5E2AQ24301563-893D25C3-432C-46B0-88FB-CE07C4527235Q24302505-91DB1B80-BB15-4FAA-A905-4CE58B66E604Q24303619-ED2FEFF2-6CA9-4B25-BFAE-F2A5DD9F7C69Q24306193-C6E804C2-D716-4637-BF11-B27E8E056723Q24306505-076C84A7-29C7-4D3A-8FD5-9FE0110A1817Q24307502-F212ECA5-15A8-4264-A3BA-DCA4864EB0FAQ24308843-6DEAC0CD-B0F7-4776-83B4-5806D2C99F04Q24310085-C8D44744-92A2-4BA0-A234-C98F6BA8E5CDQ24311403-68EEB39C-6FE5-4EE0-A290-471ED4BD94FFQ24311413-9A7E6563-40A8-4191-9364-96F064E1F683Q24312050-9C98C9BA-3DD4-4E2A-9028-4CF41704461BQ24313512-F90A15A5-68AE-4C4B-A571-5F5F5A80E29EQ24314325-8CABF0AC-6256-43DF-A689-D186ABDBFC86Q24314383-57EFA412-DA93-421C-8FA5-202FBAF9B41BQ24314411-05371208-2760-4515-8C7F-42000C25850DQ24314485-581AE0E5-37EB-47B6-A836-F509A813C3E0Q24314763-CEB27AD7-4E09-44B3-BAB3-495434A9C1CDQ24316175-D4631CBD-9CA8-4AA6-B997-12D73E1B4135Q24318682-946302EC-6014-4C42-9673-4F4DA0FFCE96Q24318769-DD45B55E-8DAE-4570-B02C-E45708F50A42
P921
description
Interacting selectively and no ...... nzyme, any of the E3 proteins.
@en
moleculaire functie
@nl
name
UB
@he
ubikitina proteinaren ligasa lotura
@eu
ubiquitin protein ligase binding
@en
unió de la proteïna de la ubiquitina
@ca
type
label
UB
@he
ubikitina proteinaren ligasa lotura
@eu
ubiquitin protein ligase binding
@en
unió de la proteïna de la ubiquitina
@ca
altLabel
GO:0031625
@en
ubiquitin ligase binding
@en
prefLabel
UB
@he
ubikitina proteinaren ligasa lotura
@eu
ubiquitin protein ligase binding
@en
unió de la proteïna de la ubiquitina
@ca
P2888
P686
GO:0031625