about
P688
The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinasesPhosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective functionCdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationNESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationAbl family kinases regulate endothelial barrier function in vitro and in miceWerner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distributionCockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinasec-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damageCharacterization of a novel member of the DOK family that binds and modulates Abl signalingCytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylationAbl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinaseRegulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylationMultiple signaling interactions of Abl and Arg kinases with the EphB2 receptorIdentification of a ten-amino acid proline-rich SH3 binding siteEssential roles for the Abl and Arg tyrosine kinases in neurulationNF-kappaB activity is constitutively elevated in c-Abl null fibroblastsc-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expressionInhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexesc-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activationCritical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cellsBone marrow B lymphocyte development in c-abl-deficient micePhosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesisThe cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene productsc-Abl phosphorylates Dok1 to promote filopodia during cell spreadingc-Abl is required for development and optimal cell proliferation in the context of p53 deficiencySHP-2 is a novel target of Abl kinases during cell proliferation.Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogeneAbl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survivalAbnormal peripheral lymphocyte function in c-abl mutant miceInactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Ablc-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesisAbl family kinases regulate FcγR-mediated phagocytosis in murine macrophagesFunctional interaction between DNA-PK and c-Abl in response to DNA damageMena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamicsAbelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylationNuclear-cytoplasmic shuttling of C-ABL tyrosine kinaseModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionDefective T cell development and function in the absence of Abelson kinases
P921
Q24290638-65D54F8D-D736-49CE-988D-8D18C9743578Q24291294-073E3FAA-4F19-449C-9CCC-F03500E5C861Q24294546-43E2D2A4-2856-47B0-813F-B8C5BCDB9100Q24298958-99143186-AC8F-4C95-A891-3C1F41E394FFQ24314378-17DBADA7-DEAC-49A1-8E61-47426ECB84A6Q24314785-3EF4B854-5C76-4B7A-AECF-B946BA396C4FQ24316240-2260B88C-8E96-4048-A812-F20277CC9F29Q24318820-508747EA-DC1D-4F5A-9DB5-7D48D4AE7014Q24318851-CAD8109F-3955-4C93-B71D-DCD8A28F9450Q24338416-4FA08620-A66C-4B28-BB47-2D080F58D8CDQ24554382-FEB2D158-A4AD-4EE9-9179-3F97C0FA8373Q28143462-B4410A98-57D0-4D56-8770-8E5F4C57BDE6Q28188375-1D48C114-334D-46F5-99A6-B26F0036F7D1Q28207600-93745869-A360-4099-AA10-94997308931AQ28211704-518CFBDF-FEE5-4CF5-BA48-5551F2A25A05Q28266446-2A67E277-A426-4A59-A49D-D6A5B4A19FC1Q28504693-93586413-4F25-4F92-A4B1-35E00C3CC5A7Q28504787-1B7F228B-50EF-43CF-8A31-7432915FD559Q28504995-4E30423C-1521-4BB3-838C-DDBA893F6C2FQ28506023-CBF4A102-2A7D-4B18-8D0B-8060A806CA0BQ28506879-EA3D2E58-4318-4C20-89FB-7057C2279E52Q28507144-AC358ECB-4742-490C-9213-8E0D83348285Q28507184-58EE913D-4303-4A96-8595-25EBA26AC1DEQ28508048-B3791B04-9DB5-4C62-BE6E-6E33AB9C29C0Q28508496-4CA660E1-EDE5-48D8-8B25-6E3415804F23Q28510526-7140C5D9-E79F-48C0-A6A3-2A8440ABF863Q28511871-60A1E967-5033-4020-A2EC-5FC279312ACAQ28512136-2E934D0C-CF1F-43CD-8FF2-D1C08777D2D5Q28512170-D3C5F221-7095-427C-BF95-0432FAD8B8B2Q28586705-B99B564B-FCF3-402C-8DD2-44A82D5EFF46Q28588624-9A31A0AB-026F-4E48-AA30-4A893560F6B6Q28588928-B901952F-A4F5-464A-854B-CC900EF4E7F8Q28589079-98C65EFE-ABAF-40BC-91A7-F17BF863D502Q28589492-D4C1C11C-421A-4D9D-A5F6-2F95911BD170Q28590355-91FB5F27-B3DB-41FA-84FA-36E44B03D4A9Q28590972-BC7E7F80-E69D-4AFC-A744-C8FC21D26F41Q28591249-9923A1D8-DEE1-42F4-93A3-2E3A01B789E0Q28591266-BCA7EFE5-9D9D-4C9C-8B72-7325E0C87005Q28591494-100A62A6-16F4-41DA-9F2E-A3F545E60C43Q28591971-4EF8252F-4659-47CA-9F22-7EF4BC89A368
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in C-abl oncogene 1, non-receptor tyrosine kinase
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
C-abl oncogene 1, non-receptor tyrosine kinase
@en
C-abl oncogene 1, non-receptor tyrosine kinase
@nl
type
label
C-abl oncogene 1, non-receptor tyrosine kinase
@en
C-abl oncogene 1, non-receptor tyrosine kinase
@nl
altLabel
Abelson murine leukemia oncogene
@en
Abelson tyrosine-protein kinase 1
@en
Abl1
@en
abelson murine leukemia viral oncogene homolog 1
@en
c-abl oncogene 1, receptor tyrosine kinase
@en
c-abl protein, type I
@en
c-abl protein, type II
@en
c-abl protein, type III
@en
p150
@en
proto-oncogene c-Abl
@en
prefLabel
C-abl oncogene 1, non-receptor tyrosine kinase
@en
C-abl oncogene 1, non-receptor tyrosine kinase
@nl
P361
P527
P637
P638
P680
P681
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P705
P352
P279
P31
P352
P361
P527
P637
NP_001106174
NP_001269974
NP_001269975
NP_001269976
XP_006497684
P638
P680
P681
P682
P702
P703
P705
ENSMUSP00000028190
ENSMUSP00000075167
ENSMUSP00000117748
ENSMUSP00000141320
ENSMUSP00000142123
ENSMUSP00000142297