about
Lymphocyte protein tyrosine kinaseHistocompatibility 2, Q region locus 10H-2 class I histocompatibility antigen, alpha chainHistocompatibility 2, D region locus 1H-2 class I histocompatibility antigen, D-D alpha chainH-2 class I histocompatibility antigen, K-D alpha chainH-2 class I histocompatibility antigen, K-W28 alpha chainH-2 class I histocompatibility antigen, K-K alpha chainH-2 class I histocompatibility antigen, D-K alpha chainH-2 class I histocompatibility antigen, D-P alpha chainH-2 class I histocompatibility antigen, K-Q alpha chainHistocompatibility 2, Q region locus 7Histocompatibility 2, K1, K regionFyn proto-oncogeneFYN proto-oncogene, Src family tyrosine kinaseHistocompatibility 2, M region locus 3Histocompatibility 2, Q region locus 6Major histocompatibility complex, class I, GFYN proto-oncogene, Src family tyrosine kinaseLCK proto-oncogene, Src family tyrosine kinase
P680
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complexHuman inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-GPolymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.
P921
Q14885208-1BCE73B4-6201-4DC6-9129-98FF085B810CQ14906955-FB0497D3-F477-4CB9-BC54-AC7B4942A9CFQ21421215-75937E44-5895-4C23-97C3-E45B47394DD3Q21421218-60AE6F07-04F5-4D96-B91E-2EAA046C4522Q21421220-F36060ED-DAFD-4279-9CC4-99F4F1D9082CQ21421222-A521EA69-8053-42B4-A70F-DE7579CBBB84Q21421223-B03E2B8F-A35A-439C-BBA0-D8A2F0D1F61DQ21421225-F20C0298-1787-4A96-8862-DB54C896D609Q21421227-BB81E598-25D4-41B6-B88B-2BC26EA2DC66Q21421229-28A2F1A6-7CF8-401A-B980-C48EFAF69BE7Q21421230-B6CFA36D-1120-4A19-BDAA-7D5F98490411Q21421232-A7665E63-C533-4B7E-BCDE-370299E0D67FQ21433498-E884E070-1BBE-4908-887B-80F617E4C945Q21984751-A5F10167-FF9A-44A0-A055-FE9017D408CBQ21984751-D95FB206-007F-4B1B-800D-9EDFD09295B7Q28559536-83E3D0DC-EB10-4615-9800-BDC810B7E2AEQ29529273-596102EC-1250-4FF2-B589-69E3D84B7DCFQ29530754-10B8ED6D-35AB-483A-88D0-826B4FEB45F8Q3124896-78EC73AA-38E1-4058-BEB9-1499A4E6CDB1Q423628-25F1F752-18A5-40BC-9770-016F95AD33BDQ9020944-8D6FBE8A-F2A0-402D-9BB2-4BE6C2C5FF36
P680
description
Interacting selectively and no ...... and suppressor T-lymphocytes.
@en
moleculaire functie
@nl
name
CD8 receptor binding
@en
type
label
CD8 receptor binding
@en
altLabel
GO:0042610
@en
prefLabel
CD8 receptor binding
@en
P279
P2888
P686
GO:0042610