about
GLI-Kruppel family member GLI3Runt related transcription factor 2Potassium channel tetramerization domain containing 6Serpin family E member 2Glypican 3TUB like protein 3GLIS family zinc finger 2G protein-coupled receptor 37 like 1RB transcriptional corepressor 1Modulator of smoothenedMultiple EGF like domains 8Potassium channel tetramerization domain containing 21Potassium channel tetramerization domain containing 11Kinesin family member 7Beta-transducin repeat containing E3 ubiquitin protein ligaseMahogunin ring finger 1Intraflagellar transport 122Unc-51 like kinase 3Spalt like transcription factor 3Hedgehog interacting proteinPatched 1Patched 2Retinoblastoma 1 (Including osteosarcoma), isoform CRA_aSUFU negative regulator of hedgehog signalingFibroblast growth factor receptor 3G protein-coupled receptor 37-like 1SUFU negative regulator of hedgehog signalingMultiple EGF-like-domains 8Growth arrest specific 1Potassium channel tetramerisation domain containing 21Potassium channel tetramerisation domain containing 11CD3 antigen, epsilon polypeptideHedgehog-interacting proteinRB transcriptional corepressor 1Potassium channel tetramerisation domain containing 6Glypican 3GLIS family zinc finger 2Serine (or cysteine) peptidase inhibitor, clade E, member 2Intraflagellar transport 122Kinesin-like protein KIF7
P682
Ter94 ATPase complex targets k11-linked ubiquitinated ci to proteasomes for partial degradationSCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.HERC4 exerts an anti-tumor role through destabilizing the oncoprotein Smo
P921
Q14886933-42F6F403-619D-4094-86D5-529CBF0B8F9DQ14907088-FDDB22A4-33F0-4B42-9FD5-9FF9525B60C6Q21096446-CCA4F194-EBA4-4F82-A265-D387ED7B47EDQ21101258-172B2C38-6BB5-4698-9D99-83FE7DAF4AD7Q21103196-A55D3F6D-4237-42CE-945D-5175061ADEEEQ21105140-03A10184-0A79-44E3-8B60-8746D516576AQ21108504-D57EFE47-0DE5-46DB-8959-8940C885CBB6Q21110197-85A45B9B-B6EA-40C0-A63F-CCAC87989540Q21111463-E236F42D-104B-4FCC-9B09-F3F5BDB7A37BQ21112012-34C7B063-9641-4295-A566-85E22896AE08Q21112734-5884B355-9F40-49F7-9CE6-EA7DB951DFEAQ21113532-CFCB9D1A-989A-4CE5-95DB-6AC38EBF4B80Q21113535-C18E2E40-46C2-4529-A4D3-C26B2C501E2AQ21114826-FDCCE2BE-1399-4781-9609-CB867CF55BADQ21116841-6AA234CA-88D3-4964-9873-8843FF99F506Q21118733-0FAC041C-97D8-41AE-9ECA-55244D6AD77FQ21119799-9524E7D2-6B73-4387-BD9B-640026D3F01FQ21124696-6CAB027E-1515-4865-9AA8-0577AD515207Q21125151-353B5351-8851-4825-BD6B-14E44E68EA09Q21132258-90B2ACDA-81E2-409D-9F36-10C1C78E2962Q21135193-3E09909A-638C-4A37-BD94-D04615F03DA0Q21135201-840D104D-8D87-469B-A57D-BDCCA65D779BQ21150360-4FA82F5B-34A0-4319-A7C5-CE5934DCCD10Q21173255-FD5D2801-CFF2-430A-8190-EDFD4DCD4130Q21421195-EDF73964-702C-4D96-86E5-CD01D09BB610Q21495597-241994BB-C982-4355-AB31-B3A3EB4EB137Q21495920-3F0908F9-9B8E-47DD-818C-BF939B0A3597Q21495920-43D81019-EEA8-4327-9249-B6F16E31490EQ21495920-5FB84E4A-4039-4FE1-9A8E-2C2B2BE9E235Q21495976-B3267EE9-1DCD-4673-933D-F6069E1F53F0Q21979959-11352522-3EAB-4AF2-AD72-AD3A71CC6AFCQ21979981-5B236CBC-A472-4F5E-B0BB-4763165B583FQ21979987-5C47C75C-E55E-4E44-80D0-A5C4E6F3A9E8Q21981008-D990C080-5B64-4B27-B23F-311693B373FCQ21982254-1CCB8593-D72A-4EA2-BE8D-67B3E285D753Q21982254-4371D729-7478-4BA5-9F67-44D8A35554C3Q21982254-906722E5-F336-49C1-9AD0-0DAC54083512Q21982891-FFFEDFE8-DAFF-455E-B810-CC643EB2C208Q21983383-56DB049C-5A9E-4EE9-A11B-0FAC497E5C5DQ21984060-9D02D594-B498-40CA-ABBF-DDB1FAD8AB3F
P682
description
Any process that stops, preven ...... xtent of smoothened signaling.
@en
biologisch proces
@nl
name
negative regulation of smoothened signaling pathway
@en
type
label
negative regulation of smoothened signaling pathway
@en
altLabel
GO:0045879
@en
down regulation of smoothened signaling pathway
@en
down-regulation of smoothened signaling pathway
@en
downregulation of smoothened signaling pathway
@en
negative regulation of hedgehog signaling pathway
@en
negative regulation of hh signaling pathway
@en
negative regulation of smoothened signalling pathway
@en
prefLabel
negative regulation of smoothened signaling pathway
@en
P2888
P686
GO:0045879