about
P688
MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomesFERM domain-containing unconventional myosin VIIA interacts with integrin β5 subunit and regulates αvβ5-mediated cell adhesion and migrationHuman Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cellsDefective myosin VIIA gene responsible for Usher syndrome type 1BMyosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) miceExpression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1BA role for myosin VI in postsynaptic structure and glutamate receptor endocytosisClass III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B proteinThe pattern of sensorineural degeneration in the cochlea of the deaf shaker-1 mouse: ultrastructural observationsElectroretinographic anomalies in mice with mutations in Myo7a, the gene involved in human Usher syndrome type 1BPHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIaNotch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathwayA Myo7a mutation cosegregates with stereocilia defects and low-frequency hearing impairmentMyosin Va is required for normal photoreceptor synaptic activityMyosin VIIa participates in opsin transport through the photoreceptor ciliumShaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cellsA forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell functionShroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctionsA core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growthCdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degenerationStereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant miceStereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant miceA type VII myosin encoded by the mouse deafness gene shaker-1alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cellsMolecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioningHes1 is a negative regulator of inner ear hair cell differentiationReduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutationsOrigin of vestibular dysfunction in Usher syndrome type 1BHEARING DEGENERATION IN SHAKER-1 MOUSE. CORRELATION OF PHYSIOLOGICAL OBSERVATIONS WITH BEHAVIORAL RESPONSES AND WITH COCHLEAR ANATOMYConditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directlyThe small GTPase Rac1 regulates auditory hair cell morphogenesis.Cattanach's translocation as a tool for studying the action of the shaker-1 gene in the mouseMutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 miceMutation analysis of the mouse myosin VIIA deafness genePhysical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cellsInteractions in the network of Usher syndrome type 1 proteinsRole of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes
P921
Q24294793-344A5AE7-8EA1-40EF-A4E5-8C88E53D4920Q24300327-D1262D0B-1585-4D39-97EC-FC8F7D87EF57Q24312049-D9F2C571-0EE8-469A-A581-33087DA7BA39Q24314638-9A50CBE9-AD00-4C9C-9453-58250706657CQ24337137-BCEB5D0D-E695-4F87-AE83-BDEF2DE6290EQ24529109-F47EE40D-E2E4-401D-9E15-852EFAC454E1Q24562934-734C090E-0738-4E54-96EA-D422B82DB0D4Q24678935-281452CE-9F17-49E0-8A55-0FF012C8A805Q27308986-D1E5DD18-A901-452C-BE64-A279F7E2A13BQ28505722-52CA4712-0618-4241-A008-0974B75917C4Q28506276-715ACE1F-DE22-4ABE-8773-B0A8250D6A25Q28506289-3BD9689A-F9B4-4327-8282-E6A14AE9167EQ28507299-6CB1F265-78B5-4993-AC22-8BD119E523C0Q28507459-5CF33ACF-5A36-482C-B212-3AD8B9889B82Q28508053-FBC5A302-FC35-49F3-866B-BD39FEB7BAAFQ28508131-15FC6A11-3048-4A68-B837-9D7C354B3E01Q28509436-D5494F2E-5527-41AF-BA55-C090F7415362Q28509764-F675B1D3-781E-483B-B8DE-6D0216526936Q28510685-E5F7F82D-EEB0-4930-99B3-67F5775B2C29Q28511375-D63FA287-55AC-487A-B044-39AAAB2C1109Q28511852-034DE77E-EDFD-4C22-B871-294E1B41D945Q28512195-0C77AE91-E878-4590-B400-703B66648338Q28512445-8C36C1C2-3AF8-480A-8472-1BE98C8AEBA5Q28512792-467CDE11-FD1B-41B2-A15C-949D99459EDFQ28512902-2336238A-CA8A-4625-81B4-E567FA03AC07Q28513517-C45D6EDE-52BC-4014-A043-A7D74C52E36EQ28513848-78B54700-EDEF-4937-86F5-9E184BCCFAC7Q28571952-867EF7E9-8ACF-4D44-B50A-7A700DE9DA16Q28586011-AC53AE6C-57F7-4D98-B335-C0FDED151CB4Q28588496-D18E823A-090F-4E2F-89DB-EFDA8DA34219Q28588694-36C0D04E-AE12-4067-99C9-305C018AA9B3Q28590666-6ECCE522-AC7A-41B7-AAA8-1660345B90DAQ28590821-2A748EDD-7C3E-4FD6-A8FD-2DE27E42F5D3Q28591364-B4267EC9-0E3C-4164-97C7-D208F414D22BQ28591603-0DA26B0E-CCE6-4452-ABC7-3858DA473239Q28591690-5067500F-5FA0-473E-AB05-9E2201F3F30CQ28592197-FB009AB1-B1F3-422A-A922-762F40028591Q28592402-DB9AB759-0594-436A-81ED-599845888F2CQ28592874-DA5D737B-3480-4EA1-8E24-9890E90E979BQ28593151-2DD56B48-0793-4FF4-A093-A07B2B6659D3
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Myosin VIIA
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Myosin VIIA
@en
Myosin VIIA
@nl
type
label
Myosin VIIA
@en
Myosin VIIA
@nl
altLabel
Myo7a
@en
motor protein
@en
myosin-VIIa
@en
shaker 1
@en
unconventional myosin-VIIa
@en
uniprot:P97479
@en
prefLabel
Myosin VIIA
@en
Myosin VIIA
@nl
P361
P527
P637
P680
P681
P682
P705
P352
P637
P638
P279
P31
P352
P361
P527
P637
NP_001243010
NP_001243011
NP_001243012
XP_006507490
XP_006507491
XP_006507492
XP_011239990
XP_011239991
XP_011239992
P680
P681
P682
P702
P703
P705
ENSMUSP00000082046
ENSMUSP00000102739
ENSMUSP00000102744
ENSMUSP00000102745
ENSMUSP00000114944
ENSMUSP00000146114
ENSMUSP00000146165
ENSMUSP00000158620
ENSMUSP00000158850