about
P688
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposinMesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formationTargeted disruption of the mouse prosaposin gene affects the development of the prostate gland and other male reproductive organsNeurological deficits and glycosphingolipid accumulation in saposin B deficient mice.Severe vestibular dysfunction and altered vestibular innervation in mice lacking prosaposinThe inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes.Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutationsThe role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin.Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.Prosaposin is a regulator of progranulin levels and oligomerization.Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking.A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse.Saposin C is required for normal resistance of acid beta-glucosidase to proteolytic degradation.Progressive deafness and altered cochlear innervation in knock-out mice lacking prosaposin.Pathological study of mice with total deficiency of sphingolipid activator proteins (SAP knockout mice).Mutation in saposin D domain of sphingolipid activator protein gene causes urinary system defects and cerebellar Purkinje cell degeneration with accumulation of hydroxy fatty acid-containing ceramide in mouseSeminolipid and its precursor/degradative product, galactosylalkylacylglycerol, in the testis of saposin A- and prosaposin-deficient miceStructural requirements for lysosomal targeting of the prosaposin precursor protein
P921
Q24293450-9E6B193B-2FE7-48BF-B665-147CA41FDC73Q24298476-1953A605-3F73-41CE-B1A2-D22542D18639Q28513106-90BAD89B-F0D8-43DF-A6C8-A3D2BEBDDB63Q28594479-5419FD4E-A035-43D1-914B-B2F57FE073C3Q30455939-733A922F-A6FA-4E67-91BF-BE5249FBA1E2Q33500402-A9744009-D5B9-4BA0-B354-31055F27C2D3Q33815765-C5B149B3-D6D4-4B3B-9080-1FC8E397700EQ33886809-B9A2F492-6AB0-4F3D-910B-98573D8A8297Q34053547-74204467-F4AE-470D-BEA2-C7D685BC99C8Q36078240-127B72C8-153C-42CA-9138-A001B9DA1035Q38847140-B73912D4-6FB3-4797-9379-ED3A3555D2F9Q42165293-61351DB1-97DE-4E3E-A4CA-2B243DF20A71Q43616427-2A6FA373-CD55-4416-8316-22951A39DFF0Q44482194-475EAEB5-5B3D-46EF-90B8-52A2C24A402BQ46425316-5363BFA4-5E37-4521-A6D5-FCDE131B1B62Q47789744-44A7A78B-9832-4D99-896B-F084EF829A99Q57373773-4A8C1B3D-B5E7-4B7D-829E-F5CA0951D635Q73537386-5C84382E-F20D-4B9B-AFA9-DC40852F0CFDQ73682048-C718FEF0-49E9-4CFC-B340-B3D417C93B2B
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Prosaposin
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Prosaposin
@en
Prosaposin
@nl
type
label
Prosaposin
@en
Prosaposin
@nl
altLabel
Psap
@en
SGP-1
@en
prosaposin
@en
snoRNA MBII-198
@en
sulfated glycoprotein 1
@en
prefLabel
Prosaposin
@en
Prosaposin
@nl
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NP_001139592
NP_001139593
NP_001139594
NP_001139595
NP_001139596
XP_017169337
XP_017169338
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ENSMUSP00000004316
ENSMUSP00000101105
ENSMUSP00000126407
ENSMUSP00000137286
ENSMUSP00000137476