about
P688
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNAT-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factorsRole of the LXXLL-motif and activation function 2 domain in subcellular localization of Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1)The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis developmentTpit determines alternate fates during pituitary cell differentiationTranscriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1)Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis developmentDax-1 as one of the target genes of Ad4BP/SF-1Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine developmentDifferential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine functionSOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitroLack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cellsCell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal functionNovel markers of early ovarian pre-granulosa cells are expressed in an Sry-like patternNuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta geneAntagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in miceAdrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activationThe transcription co-factor CITED2 functions during sex determination and early gonad developmentInteraction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1
P921
Q22254231-9D4F66F9-21A0-4BD3-BB18-13DBA231894FQ24681142-9836BD8B-19C7-459E-BE95-7C5D924048FDQ28505648-080A5443-F736-478E-A436-81008DAA89E5Q28506797-B06EA804-3F48-4CAB-8F52-65EC6CC3DA54Q28508185-46317D3F-F382-4BD4-A806-0FB7D0E0E249Q28510034-5CE4734E-A73C-4358-9B4B-6ABFA7F3EDB1Q28510433-33130129-C359-4CDA-920D-EC8824C4C4A0Q28512958-6FFD37C5-20B6-486D-9049-8A00B3B36E6DQ28513287-6A33F4D9-96C0-4A12-837B-A4B22BC24129Q28513980-7FC623AF-FE84-4F01-A54C-6529304961EDQ28589100-6EAC1EDF-909E-47D4-AA26-7A9F209336A9Q28589760-7851E5C1-398E-4FCD-BDF5-42540BE9025EQ28590881-2B12ACB5-4986-4095-8766-27162BC94193Q28590895-9FA5AED1-5557-4173-AA8B-FA8C3D8496F0Q28591693-5FEF52FF-0493-431D-951F-293B3B197726Q28593808-E129DAFD-7605-4235-B9AB-2AD4B6935435Q28594208-31A9BCA7-D46A-4E0D-99F0-D8BE3B087132Q28594232-C71B0546-DAEB-4074-85E3-CF8056538CAEQ28594777-C3E491F3-58E5-4CB0-90F0-2A7490D433D8
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Nuclear receptor subfamily 5, group A, member 1
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Nuclear receptor subfamily 5, group A, member 1
@en
type
label
Nuclear receptor subfamily 5, group A, member 1
@en
altLabel
ELP
@en
Nr5a1
@en
Nuclear receptor subfamily 5 group A member 1
@en
adrenal 4-binding protein
@en
embryonal LTR-binding protein
@en
embryonal long terminal repeat-binding protein
@en
fushi tarazu 1 factor homolog
@en
fushi tarazu factor homolog 1
@en
steroid hormone receptor Ad4BP
@en
steroid hydroxylase positive regulator
@en
prefLabel
Nuclear receptor subfamily 5, group A, member 1
@en
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P31
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NP_001303616
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ENSMUSP00000028084
ENSMUSP00000108504