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Shifting the polarity of some critical residues in malarial peptides' binding to host cells is a key factor in breaking conserved antigens' code of silenceThe effect of flavonol glycosides on opiate withdrawalThe preparation and human muscarinic receptor profiling of oxybutynin and N-desethyloxybutynin enantiomersIn search of new cures for tuberculosisThe effects of interleukin-10 on the expression of Fas and FasL in rat hepatic stellate cellsAdvances in protein contact map prediction based on machine learning.Design, synthesis and in-vivo hypoglycemic evaluation of novel non - TZD'S in a type - 2 diabetic model.Chemometric Analysis of Some Biologically Active Groups of Drugs on the Basis Chromatographic and Molecular Modeling Data.Synthesis and evaluation of a novel gene reporter molecule: detection of beta-galactosidase activity using 19F NMR of a fluorinated vitamin B6 conjugate+.Synthesis and Biological Evaluation of Hybrid 1,5- and 2,5-Disubstituted Indoles as Potentially New Antitubercular Agents.DNA and RNA aptamers as modulators of protein function.Interaction field based and hologram based QSAR analysis of propafenone-type modulators of multidrug resistance.ICG-001, a novel small molecule regulator of TCF/beta-catenin transcription.New cysteine derivatives with antiproliferative activity on melanoma cells.Drug evolution concept in drug design: 2. Chimera method.A new nucleotide-composition based fingerprint of SARS-CoV with visualization analysis.A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology.Biophysical characterization of the interaction of endotoxins with hemoglobins.An in silico 3D pharmacophore model of chalcones useful in the design of novel antimalarial agents.N-acetylcysteine exerts protective effects and prevents lung redox imbalance and peroxynitrite generation in endotoxemic rats.Processing of small molecule databases for automated docking.Therapeutic roles of heparin anticoagulants in cancer and related disorders.Novel cell nucleus directed fluorescent tetraazacyclododecane-tetra-acetic acid compounds.Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent.Novel 2-hydrazino-pyrimidin-4(3H)-one derivatives with pseudofunctional- similarity to siderophores as potential antimycobacterial agents.Anticancer activity of the ascidian polyclinum indicum against cervical cancer cells (HeLa) mediated through apoptosis induction.Synthesis, testing and structure-activity studies on a library of 5-HT₄ ligands.Exploring QSAR, pharmacophore mapping and docking studies and virtual library generation for cycloguanil derivatives as PfDHFR-TS inhibitors.Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent.Oseltamivir: a first line defense against swine flu.Syntheses of 2,3-diarylated 2H-benzo[e][1,2]thiazine 1,1-dioxides and their 3,4-dihydro derivatives, and assessment of their inhibitory activity against MCF-7 breast cancer cells.Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2.Novel gastrin receptor-directed contrast agents - potential in brain tumor magnetic resonance imaging.Optimization of important early ADME(T) parameters of NADPH oxidase-4 inhibitor molecules.Mechanism of pain relief by low-power infrared irradiation: ATP is an IR-target molecule in nociceptive neurons.Modulation of signal-transducing function of neuronal membrane Na+,K+-ATPase by endogenous ouabain and low-power infrared radiation leads to pain relief.Antibacterial activity of thyme and lavender essential oils.Synthesis and study the analgesic effects of new analogues of ketamine on female wistar rats.Prediction of allergenic proteins by means of the concept of Chou's pseudo amino acid composition and a machine learning approach.3D QSAR pharmacophore, CoMFA and CoMSIA based design and docking studies on phenyl alkyl ketones as inhibitors of phosphodiesterase 4.
P1433
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P1433
description
journal
@en
revista científica
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rivista scientifica
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wetenschappelijk tijdschrift van Bentham Science Publishers
@nl
wissenschaftliche Fachzeitschrift
@de
name
Medicinal Chemistry
@ast
Medicinal Chemistry
@da
Medicinal Chemistry
@en
Medicinal Chemistry
@es
Medicinal Chemistry
@fi
Medicinal Chemistry
@fr
Medicinal Chemistry
@it
Medicinal Chemistry
@nb
Medicinal Chemistry
@nl
Medicinal Chemistry
@nn
type
label
Medicinal Chemistry
@ast
Medicinal Chemistry
@da
Medicinal Chemistry
@en
Medicinal Chemistry
@es
Medicinal Chemistry
@fi
Medicinal Chemistry
@fr
Medicinal Chemistry
@it
Medicinal Chemistry
@nb
Medicinal Chemistry
@nl
Medicinal Chemistry
@nn
prefLabel
Medicinal Chemistry
@ast
Medicinal Chemistry
@da
Medicinal Chemistry
@en
Medicinal Chemistry
@es
Medicinal Chemistry
@fi
Medicinal Chemistry
@fr
Medicinal Chemistry
@it
Medicinal Chemistry
@nb
Medicinal Chemistry
@nl
Medicinal Chemistry
@nn
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Medicinal Chemistry
@und