Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?
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Thiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease modelsIdentification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugsComparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidatesGenome comparison of human and non-human malaria parasites reveals species subset-specific genes potentially linked to human disease.Predictive Genomic Analyses Inform the Basis for Vitamin Metabolism and Provisioning in Bacteria-Arthropod EndosymbiosesCINPER: an interactive web system for pathway prediction for prokaryotesFrom microbial gene essentiality to novel antimicrobial drug targetsPrediction of vitamin interacting residues in a vitamin binding protein using evolutionary information.Quantitative genome-wide genetic interaction screens reveal global epistatic relationships of protein complexes in Escherichia coliHabitat visualization and genomic analysis of "Candidatus Pantoea carbekii," the primary symbiont of the brown marmorated stink bug.Imaging metabolite dynamics in living cells using a Spinach-based riboswitch.Comparative Analysis of Lacinutrix Genomes and Their Association with Bacterial HabitatMolecular Mechanisms Contributing to the Growth and Physiology of an Extremophile Cultured with Dielectric Heating.Pre- and post-weaning diet alters the faecal metagenome in the cat with differences vitamin and carbohydrate metabolism gene abundancesAssessment of intake and nutritional status of vitamin b1, b2, and b6 in men and women with different physical activity levelsProteomics of rice in response to heat stress and advances in genetic engineering for heat tolerance in rice.Riboswitch structure in the ligand-free state.Speculative strategies for new antibacterials: all roads should not lead to Rome.Multiple mutations and increased RNA expression in tetracycline-resistant Streptococcus pneumoniae as determined by genome-wide DNA and mRNA sequencing.Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase.Systematic discovery of drug interaction mechanisms.Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS.Thiamine antivitamins--an opportunity of therapy of fungal infections caused by Malassezia pachydermatis and Candida albicans.Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases.Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis.Underlying mechanisms for syntrophic metabolism of essential enzyme cofactors in microbial communities.Conformational dynamics of 1-deoxy-d-xylulose 5-phosphate synthase on ligand binding revealed by H/D exchange MS.Phage Display on the Anti-infective Target 1-Deoxy-d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor.Inhibition of proteases and phospholipases A2 from Bothrops atrox and Crotalus durissus terrificus snake venoms by ascorbic acid, vitamin E, and B-complex vitamins.Comparative genome analysis of the Flavobacteriales bacterium strain UJ101, isolated from the gut of Atergatis reticulatus.Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors.The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation.Carboxythiazole is a key microbial nutrient currency and critical component of thiamin biosynthesis.The MEP pathway and the development of inhibitors as potential anti-infective agents
P2860
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P2860
Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@ast
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en-gb
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@nl
type
label
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@ast
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en-gb
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@nl
prefLabel
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@ast
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en-gb
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@nl
P2093
P2860
P921
P356
P1476
Thiamin (vitamin B1) biosynthe ...... of antimicrobial drug targets?
@en
P2093
Honghai Wang
Jianping Xie
Qinglin Du
P2860
P356
10.7150/IJBS.7.41
P407
P577
2011-01-09T00:00:00Z