Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs - Test2 - elhamkhani - TriplyDB

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs

http://www.wikidata.org/entity/Q21089606

about

Novel adjunctive therapies for the treatment of tuberculosis Tuberculosis drug discovery in the post-post-genomic era Rising to the challenge: new therapies for tuberculosis TB drug development: immunology at the table Persistent high mortality in advanced HIV/TB despite appropriate antiretroviral and antitubercular therapy: an emerging challenge New insights into TB physiology suggest untapped therapeutic opportunities Tuberculosis vaccines: barriers and prospects on the quest for a transformative tool Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth New tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeutics Etanercept exacerbates inflammation and pathology in a rabbit model of active pulmonary tuberculosis Augmented annotation and orthologue analysis for Oryctolagus cuniculus: Better Bunny Simvastatin increases the in vivo activity of the first-line tuberculosis regimen.Advancing host-directed therapy for tuberculosis.Tuberculosis, pulmonary cavitation, and matrix metalloproteinases.Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection Cytokine and lipid mediator networks in tuberculosis Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages.Roflumilast, a Type 4 Phosphodiesterase Inhibitor, Shows Promising Adjunctive, Host-Directed Therapeutic Activity in a Mouse Model of Tuberculosis.Spontaneous latency in a rabbit model of pulmonary tuberculosis.Adjunctive Phosphodiesterase-4 Inhibitor Therapy Improves Antibiotic Response to Pulmonary Tuberculosis in a Rabbit Model.Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis.Adjuvant host-directed therapy with types 3 and 5 but not type 4 phosphodiesterase inhibitors shortens the duration of tuberculosis treatment Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis.Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits The granuloma in tuberculosis: dynamics of a host-pathogen collusion.Host-directed therapeutics for tuberculosis: can we harness the host?Chemical activation of adenylyl cyclase Rv1625c inhibits growth of Mycobacterium tuberculosis on cholesterol and modulates intramacrophage signaling.Host-Directed Therapies for Tuberculosis.A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection.Detection of Mycobacterium tuberculosis in latently infected lungs by immunohistochemistry and confocal microscopy.Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue.Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response.Addressing the Challenges of Tuberculosis: A Brief Historical Account.Host-Directed Therapeutic Strategies for Tuberculosis.Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials.Harnessing the mTOR Pathway for Tuberculosis Treatment.Effect of Mycobacterium tuberculosis infection on adipocyte physiology.Comparison of gene expression profiles between pansensitive and multidrug-resistant strains of Mycobacterium tuberculosis.Translational Potential of Therapeutics Targeting Regulatory Myeloid Cells in Tuberculosis

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P2860

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs

http://www.wikidata.org/entity/Q21089606

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年論文

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2011年論文

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Phosphodiesterase-4 inhibition ...... m tuberculosis in rabbit lungs

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Phosphodiesterase-4 inhibition ...... m tuberculosis in rabbit lungs

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Blas Peixoto

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P2860

False beliefs about fattening foods can have healthy consequences

Toll-like receptor signalling

Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition

PDE4 inhibitors: current status

Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications

Multiple cyclic nucleotide phosphodiesterases

Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation

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e1002262

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10.1371/JOURNAL.PPAT.1002262

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Selvakumar Subbian

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51665581

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21949656

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Mycobacterium tuberculosis

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