Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular dynamics simulation
about
Rational approaches to improving selectivity in drug designSerendipitous alkylation of a Plk1 ligand uncovers a new binding channelA novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.Achieving peptide binding specificity and promiscuity by loops: case of the forkhead-associated domain.Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains.Peptide-based inhibitors of Plk1 polo-box domain containing mono-anionic phosphothreonine esters and their pivaloyloxymethyl prodrugs.Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes.Correlations in liquid water for the TIP3P-Ewald, TIP4P-2005, TIP5P-Ewald, and SWM4-NDP models.The conformational feasibility for the formation of reaching dimer in ASV and HIV integrase: a molecular dynamics study.Rational Molecular Design of Potent PLK1 PBD Domain-binding Phosphopeptides Using Preferential Amino Acid Building Blocks.Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction Surface.A Role for Hydration in Interleukin-2 Inducible T Cell Kinase (Itk) Selectivity.
P2860
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P2860
Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular dynamics simulation
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Computational analysis of phos ...... molecular dynamics simulation
@ast
Computational analysis of phos ...... molecular dynamics simulation
@en
Computational analysis of phos ...... molecular dynamics simulation
@en-gb
Computational analysis of phos ...... molecular dynamics simulation
@nl
type
label
Computational analysis of phos ...... molecular dynamics simulation
@ast
Computational analysis of phos ...... molecular dynamics simulation
@en
Computational analysis of phos ...... molecular dynamics simulation
@en-gb
Computational analysis of phos ...... molecular dynamics simulation
@nl
altLabel
Computational Analysis of Phos ...... Molecular Dynamics Simulation
@en
prefLabel
Computational analysis of phos ...... molecular dynamics simulation
@ast
Computational analysis of phos ...... molecular dynamics simulation
@en
Computational analysis of phos ...... molecular dynamics simulation
@en-gb
Computational analysis of phos ...... molecular dynamics simulation
@nl
P2093
P2860
P1476
Computational analysis of phos ...... molecular dynamics simulation
@en
P2093
Ana J Narváez
Ashok R Venkitaraman
Bryn Hardwick
Daniel D Robinson
Grahame J McKenzie
Guy H Grant
Meredith Roberts-Thomson
Mike C Payne
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000880
P407
P577
2010-01-01T00:00:00Z