Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
about
P688
Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocationStructure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartmentCrystal structures of the BAR-PH and PTB domains of human APPL1Loss-of-Function Mutations in APPL1 in Familial Diabetes MellitusMembrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides.Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cellsInteractions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle.Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment.Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription.
P921
Q22010548-F322A593-D4C8-4246-85C6-4AC848A12A28Q24293287-BA7D250A-15E8-4CAC-B2BF-4B40C29F26EBQ24312202-36DA998D-CCC6-4899-BE64-CBECB7E2301FQ24316183-005D164F-5AB6-48FA-90A1-493CC8740610Q27644770-4D7E04E6-65CF-47D3-9DB5-8487CFB79B39Q28115902-B9C8BC2B-1C24-4359-AED1-B92FA77A8566Q30555227-C5875BD6-8491-4CC2-A700-1F429731072FQ33553662-7D4FA577-708D-4B12-A24C-E13A367AE215Q35146459-E15B083E-20C8-484A-A386-2DA418058BECQ36729386-C4DF837A-FC70-472A-BAF4-65D77EED27BBQ38989847-7D72213B-68DA-4505-99DA-5C7D7D28DC15Q42210260-5F8F3869-9B99-46E7-85D8-4F78F121D8E2Q43095790-B874C62F-91CD-41CF-AAAE-695288F88C2A
P921
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Adaptor protein, p ...... PH domain and leucine zipper 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
@en
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
@nl
type
label
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
@en
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
@nl
altLabel
AKT2 interactor
@en
APPL1
@en
DCC-interacting protein 13-alpha
@en
adapter protein containing PH domain, PTB domain and leucine zipper motif 1
@en
adaptor protein containing pH domain, PTB domain and leucine zipper motif 1
@en
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
@en
dip13-alpha
@en
signaling adaptor protein DIP13alpha
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prefLabel
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
@en
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
@nl
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ENSP00000288266
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