about
Cytochrome c oxidase copper chaperone COX17Cytochrome c oxidase assembly factor COX19Cytochrome c oxidase assembly factor COX18Cytochrome c oxidase assembly factor COX14Translocase of inner mitochondrial membrane 21Cytochrome c oxidase assembly factor COX16FAST kinase domains 3SURF1 cytochrome c oxidase assembly factorCytochrome c oxidase assembly factor 4 homologCytochrome c oxidase assembly factor 3Cytochrome c oxidase assembly factor COX20BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperoneOXA1L mitochondrial inner membrane proteinPET100 cytochrome c oxidase chaperonePET117 cytochrome c oxidase chaperoneCytochrome c oxidase assembly factor 5Cytochrome c oxidase assembly factor 1 homologCoiled-coil-helix-coiled-coil-helix domain containing 5Synthesis of cytochrome C oxidase 2Synthesis of cytochrome C oxidase 1Small integral membrane protein 20BCS1-like (yeast)Cytochrome c oxidase assembly protein 14Cytochrome c oxidase assembly protein 17, copper chaperoneCytochrome c oxidase assembly protein 19Cytochrome c oxidase assembly protein 18Cytochrome c oxidase assembly protein 16Oxidase assembly 1-likeCytochrome c oxidase assembly protein 20Coiled-coil-helix-coiled-coil-helix domain containing 5Cytochrome c oxidase assembly factor 4Cytochrome C oxidase assembly factor 5Cytochrome C oxidase assembly factor 3FAST kinase domains 3Surfeit gene 1SCO1 cytochrome c oxidase assembly proteinSCO2 cytochrome c oxidase assembly proteinTranslocase of inner mitochondrial membrane 21PET100 homologPET117 homolog
P682
Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidaseMutations in C12orf62, a factor that couples COX I synthesis with cytochrome c oxidase assembly, cause fatal neonatal lactic acidosisMITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase AssemblySURF1 deficiency causes demyelinating Charcot-Marie-Tooth diseaseHuman COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase.Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module.A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia.COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.COX16 is required for assembly of cytochrome c oxidase in human cells and is involved in copper delivery to COX2.
P921
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P682
Q21184006-F1F42500-1FFA-4EDD-9D95-EAC22D0381A0Q24301791-FE6E4B6C-B3D9-4483-85DC-A8944F71DA00Q28115839-435B9F01-4AC0-496A-A3C2-42A496E0D619Q28118095-98D133B7-FFC6-4BE9-AB3C-60AC60D8DCDBQ33582770-A3B4E096-CC7A-4B19-9CA5-6B018F6D1302Q38711145-DFC0420E-2F7B-4A91-BC45-20C462DB8E9EQ47074411-AFE988C9-DEDA-4FFF-B560-F0B2D69673A1Q47643939-79B8ABBF-2467-449E-879D-035AA2ED85EFQ47651551-25683575-072C-4EDB-9E21-8FEBD8B4E56E
P921
description
The aggregation, arrangement a ...... mitochondrial inner membrane.
@en
biologisch proces
@nl
name
mitochondrial respiratory chain complex IV assembly
@en
type
label
mitochondrial respiratory chain complex IV assembly
@en
altLabel
GO:0033617
@en
mitochondrial cytochrome c oxidase complex assembly
@en
mitochondrial respiratory chain complex IV assembly
@en
prefLabel
mitochondrial respiratory chain complex IV assembly
@en
P2888
P686
GO:0033617