about
P688
Replication protein A stimulates long patch DNA base excision repairStructure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPAReplication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeresCellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpointsStructure of the single-stranded-DNA-binding domain of replication protein A bound to DNARPA involvement in the damage-recognition and incision steps of nucleotide excision repairEvidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNAFunctional domains of the 70-kilodalton subunit of human replication protein ASumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodiesThe evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repairRPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cellsWDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA DamageActivation of the ATR kinase by the RPA-binding protein ETAA1ETAA1 acts at stalled replication forks to maintain genome integrityHuman replication protein A unfolds telomeric G-quadruplexesRPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome endsBinding polarity of RPA to telomeric sequences and influence of G-quadruplex stability
P921
Q22003913-C6B51462-F6A2-4A32-8FB1-2D88ED3CB1EBQ24293001-8B835811-C715-4194-B77A-D255868AB75DQ24298583-17548774-111C-4745-8698-B9E05E07647BQ24311398-B65750DA-41D2-4988-856B-6E5456CECE4EQ24311910-E95F9110-16FD-44B2-949A-FA5C1118DD6DQ24312764-17ED6AC2-D7C3-4509-8D5B-EE3123796556Q24314908-EDC0E6C5-08EE-4FFF-BF66-B68DAC9EEF25Q24316316-B58FA24C-1D8C-4FC8-AA4C-471A5E87FEA8Q24319535-F479AC36-0D40-4A7E-A3D4-3CD1A86F1515Q24321288-4A2A2842-178E-413D-BA32-983F71336FE1Q24338859-7F0B8B5B-F9AC-447F-8DDA-DEE1DD0E8F25Q27346818-EFB2E477-D5BF-42FE-8D73-C76C360217BFQ28596569-8DB203E5-0C3E-43E5-9049-35AE1AD15A6BQ28596606-718F3E63-846D-48DD-B1FA-2ADAD8D95D84Q29147418-5331E397-6AA8-4336-B9C9-C2BE997940A1Q29147430-0D0970D9-A057-4B84-A1F7-2D5FDD7AEA07Q29147561-E58DDE3B-33C2-4676-9CE2-09940609949E
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Replication protein A1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Replication protein A1
@en
Replication protein A1
@nl
type
label
Replication protein A1
@en
Replication protein A1
@nl
altLabel
MSTP075
@en
RF-A protein 1
@en
RP-A p70
@en
RPA1
@en
replication factor A protein 1
@en
replication protein A 70 kDa DNA-binding subunit
@en
replication protein A1, 70kDa
@en
single-stranded DNA-binding protein
@en
prefLabel
Replication protein A1
@en
Replication protein A1
@nl
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NP_001342049
NP_001342050
XP_024306631
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ENSP00000254719
ENSP00000459788
ENSP00000461466
ENSP00000461733