about
P688
Expression and function of the homeodomain-containing protein Hex in thyroid cells.The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growthHEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitroThe proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cellsThyroid-specific transcription factors control Hex promoter activityThe transcriptional repressor protein PRH interacts with the proteasomeOligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domainCK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA bindingInteraction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signalingThe PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressorsDNA wrapping and distortion by an oligomeric homeodomain protein
P921
Q22254377-F1144ABA-3CDB-45E0-8BF6-C38B170AEC67Q24293421-6A6CF86D-4C0F-47CF-8CE5-5BCEAA0B9D45Q24294753-1EA98CE2-48B2-40E6-9948-6C65DA62679DQ24296022-52062BED-2E99-48CB-AF79-A23271D28A19Q24298404-08941792-DDDB-4CB8-9B7F-BC7836EDDA1AQ24306300-16C7B703-25DC-4A51-952E-8812EB7BA21BQ24307850-3391CCF9-5258-4821-A721-E402DBB57FF6Q24310110-F13AE397-8EBE-46BB-83CB-2A4C3DD29C59Q24316239-2152CA83-F9F6-44A7-AE61-BE839DC842E0Q24324330-A60479B4-7F8B-4B81-A8D5-D103DFDFCD88Q24337003-578C0DA9-AD67-4657-AAA4-8E9C130F80BB
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Hematopoietically expressed homeobox
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Hematopoietically expressed homeobox
@en
type
label
Hematopoietically expressed homeobox
@en
altLabel
HHEX
@en
hematopoietically-expressed homeobox protein HHEX
@en
homeobox protein HEX
@en
homeobox protein PRH
@en
homeobox, hematopoietically expressed
@en
proline-rich homeodomain-containing transcription factor
@en
prefLabel
Hematopoietically expressed homeobox
@en
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ENSP00000282728
ENSP00000447953
ENSP00000450017