about
P527
P688
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activityLysine glutarylation is a protein posttranslational modification regulated by SIRT5Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylaseSIRT5-mediated lysine desuccinylation impacts diverse metabolic pathwaysSirtuin functions in health and diseaseEvolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteinsSubstrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5The first identification of lysine malonylation substrates and its regulatory enzymeSIRT5 desuccinylates and activates SOD1 to eliminate ROSSHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.
P921
Q22010164-16E1EAB1-176F-4900-A4E6-ACCA7325977DQ24293721-4566BB1B-D465-47C2-ABA9-86F192DAA59CQ24296766-5A3491B8-77DC-47DA-9F4E-E5E96A8E34E1Q24296915-B113A5FE-324B-48AC-A3D8-21D9473444A1Q24303857-F344026B-A7FF-4815-9697-1ED2F8929360Q24312912-091A115C-881A-4185-A015-3BA5B08CDE6CQ24321334-B20B6DDF-7CE4-4B7E-915B-EE64AC9190C6Q24337617-5B743A91-F63A-4CC8-BAA1-66677DAF560FQ24338611-4C863AE7-E4D5-4B08-9F3D-9D619B3F0AB8Q48588768-296F4C06-7B4D-4981-A7BC-989E4430770D
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Sirtuin 5
@en
Sirtuin 5
@nl
type
label
Sirtuin 5
@en
Sirtuin 5
@nl
altLabel
NAD-dependent deacetylase sirtuin-5
@en
NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial
@en
NAD-dependent protein deacylase sirtuin-5, mitochondrial
@en
Regulatory protein SIR2 homolog 5
@en
SIR2-like protein 5
@en
SIRT5
@en
silent mating type information regulation 2, S.cerevisiae, homolog 5
@en
sir2-like 5
@en
sirtuin type 5
@en
prefLabel
Sirtuin 5
@en
Sirtuin 5
@nl
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NP_001180196
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NP_001363728
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NP_001363731
NP_001363732
NP_001363733
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ENSP00000352830
ENSP00000368552
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ENSP00000476228