Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
about
Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary propertiesNix is a selective autophagy receptor for mitochondrial clearanceLoss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinThe SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein UnkemptIBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationUbiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extensionTarget-selective protein S-nitrosylation by sequence motif recognitionAkt is negatively regulated by the MULAN E3 ligaseThe TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ERSystematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networksStructural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationMitochondrial ubiquitin ligase MITOL ubiquitinates mutant SOD1 and attenuates mutant SOD1-induced reactive oxygen species generationMitochondrially localised MUL1 is a novel modulator of antiviral signalingNedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptorMAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fissionRNF152, a novel lysosome localized E3 ligase with pro-apoptotic activitiesA comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome systemHRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradationSelective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMTHECT and RING finger families of E3 ubiquitin ligases at a glanceStructural basis for autoinhibition and phosphorylation-dependent activation of c-CblGenomic screening with RNAi: results and challengesDrugging the undruggables: exploring the ubiquitin system for drug developmentCross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and DiseaseUbiquitin proteasome system research in gastrointestinal cancerUbiquitin in the activation and attenuation of innate antiviral immunityThe Non-Canonical Role of Aurora-A in DNA ReplicationProtein degradation and the stress responseThe Pup-Proteasome System of MycobacteriaTargeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of CardiologyExpansion and diversification of BTL ring-H2 ubiquitin ligases in angiosperms: putative Rabring7/BCA2 orthologsFunctional diversity and structural disorder in the human ubiquitination pathwayGenetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination ActivitiesUbiquitin-dependent mitochondrial protein degradation.A bacterial genetic selection system for ubiquitylation cascade discoveryUbiquitin-proteasome-dependent degradation of a mitofusin, a critical regulator of mitochondrial fusion.Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.Pex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import.
P2860
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P2860
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Genome-wide and functional ann ...... nelle's dynamics and signaling
@ast
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en-gb
Genome-wide and functional ann ...... nelle's dynamics and signaling
@nl
type
label
Genome-wide and functional ann ...... nelle's dynamics and signaling
@ast
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en-gb
Genome-wide and functional ann ...... nelle's dynamics and signaling
@nl
prefLabel
Genome-wide and functional ann ...... nelle's dynamics and signaling
@ast
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en-gb
Genome-wide and functional ann ...... nelle's dynamics and signaling
@nl
P2093
P2860
P921
P3181
P1433
P1476
Genome-wide and functional ann ...... nelle's dynamics and signaling
@en
P2093
Akio Matsuda
Anthony Orth
Axel Ulbrich
Claudio A P Joazeiro
Mario H Bengtson
Sumit K Chanda
Venkateshwar A Reddy
P2860
P3181
P356
10.1371/JOURNAL.PONE.0001487
P407
P577
2008-01-01T00:00:00Z