CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease - Test2 - elhamkhani - TriplyDB

CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease

CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease

http://www.wikidata.org/entity/Q21284814

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Perspectives on anti-CD47 antibody treatment for experimental cancer Long-Term Cultures of Human Cornea Limbal Explants Form 3D Structures Ex Vivo - Implications for Tissue Engineering and Clinical Applications Polymorphisms in the Human Inhibitory Signal-regulatory Protein Do Not Affect Binding to Its Ligand CD47 CD47 expression in cryopreserved equine cutaneous masses and normal skin Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans Registered report: the CD47-signal regulated protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses.F4/80+ Host Macrophages Are a Barrier to Murine Embryonic Stem Cell-Derived Hematopoietic Progenitor Engraftment In Vivo.Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells CD47 deficiency protects mice from diet-induced obesity and improves whole body glucose tolerance and insulin sensitivity.SHP-1-dependent macrophage differentiation exacerbates virus-induced myositis Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen Erythrocyte-derived nano-probes functionalized with antibodies for targeted near infrared fluorescence imaging of cancer cells.Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy.Leukocyte recruitment in inflammation: basic concepts and new mechanistic insights based on new models and microscopic imaging technologies.Phagocytic receptors activate and immune inhibitory receptor SIRPα inhibits phagocytosis through paxillin and cofilin A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer Engineering antiphagocytic biomimetic drug carriers.BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton.Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.The CD47 "don't eat me signal" is highly expressed in human ovarian cancer.Divergent modulation of normal and neoplastic stem cells by thrombospondin-1 and CD47 signaling.Role of thrombospondin 1 in liver diseases.Optical properties of biomimetic probes engineered from erythrocytes.Acute myeloid leukemia targets for bispecific antibodies.From the Cradle to the Grave: The Role of Macrophages in Erythropoiesis and Erythrophagocytosis.Increased Apoptosis of Inflamed Odontoblasts Is Associated with CD47 Loss.How do red blood cells know when to die?Signal-regulatory protein α from the NOD mouse binds human CD47 with an exceptionally high affinity-- implications for engraftment of human cells Staphylococcus aureus proteins SSL6 and SElX interact with neutrophil receptors as identified using secretome phage display.Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation.Macrophage Clearance of Apoptotic Cells: A Critical Assessment.Red blood cells with elevated cytoplasmic Ca(2+) are primarily taken up by splenic marginal zone macrophages and CD207+ dendritic cells.Anti-human SIRPα antibody is a new tool for cancer immunotherapy.Preclinical development of a bispecific antibody that safely and effectively targets CD19 and CD47 for the treatment of B cell lymphoma and leukemia.BNIP3 promotes the motility and migration of keratinocyte under hypoxia.CD47-ligation induced cell death in T-acute lymphoblastic leukemia.BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.

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CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease

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2013 nî lūn-bûn

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Per-Arne Oldenborg

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Association of signal-regulatory proteins beta with KARAP/DAP-12

Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation

A family of proteins that inhibit signalling through tyrosine kinase receptors

Rh-related antigen CD47 is the signal-transducer integrin-associated protein

Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

CD47 regulates bone mass and tumor metastasis to bone

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

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