Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems - Test2 - elhamkhani - TriplyDB

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

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Viruses and mobile elements as drivers of evolutionary transitions Evolutionary Ecology of Prokaryotic Immune Mechanisms Nucleic acids delivery methods for genome editing in zygotes and embryos: the old, the new, and the old-new Genome-editing Technologies for Gene and Cell Therapy CRISPR-Cas: biology, mechanisms and relevance Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems Nucleic acid detection with CRISPR-Cas13a/C2c2 Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response.Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems Spacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation.Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.Genetic and epigenetic control of gene expression by CRISPR-Cas systems.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires.High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.Breaking-Cas-interactive design of guide RNAs for CRISPR-Cas experiments for ENSEMBL genomes.C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Applications of CRISPR technologies in research and beyond.New CRISPR-Cas systems from uncultivated microbes.Profile of Eugene V. Koonin Evolution of RNA- and DNA-guided antivirus defense systems in prokaryotes and eukaryotes: common ancestry vs convergence ISC, a Novel Group of Bacterial and Archaeal DNA Transposons That Encode Cas9 Homologs.Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence.Genome Editing with CRISPR-Cas9: Can It Get Any Better?RNA damage in biological conflicts and the diversity of responding RNA repair systems Comparative genomic analysis identifies structural features of CRISPR-Cas systems in Riemerella anatipestifer.Coupling immunity and programmed cell suicide in prokaryotes: Life-or-death choices.Role of Recombinant DNA Technology to Improve Life Diversity and evolution of class 2 CRISPR-Cas systems.Functional interrogation of non-coding DNA through CRISPR genome editing.Reconstruction of the evolution of microbial defense systems.Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery.CRISPR interference and priming varies with individual spacer sequences Diversity, classification and evolution of CRISPR-Cas systems.Just how Lamarckian is CRISPR-Cas immunity: the continuum of evolvability mechanisms.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research Gene Editing for Treatment of Neurological Infections.

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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

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2015 nî lūn-bûn

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2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2015 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

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Feng Zhang

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Kira S. Makarova

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Leonid Minakhin

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Omar O. Abudayyeh

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Sergey Shmakov

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Yuri I. Wolf

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A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Mfold web server for nucleic acid folding and hybridization prediction

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Cas9 as a versatile tool for engineering biology

Multiplex genome engineering using CRISPR/Cas systems

Efficient genome editing in zebrafish using a CRISPR-Cas system

MUSCLE: multiple sequence alignment with high accuracy and high throughput

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

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