Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling
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7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disordersGalectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration.Treatment with TO901317, a synthetic liver X receptor agonist, reduces brain damage and attenuates neuroinflammation in experimental intracerebral hemorrhage.A mouse model of weight-drop closed head injury: emphasis on cognitive and neurological deficiencymiR-711 upregulation induces neuronal cell death after traumatic brain injury.7,8-Dihydroxyflavone, a Tropomyosin-Kinase Related Receptor B Agonist, Produces Fast-Onset Antidepressant-Like Effects in Rats Exposed to Chronic Mild Stress.7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice.Tyrosine Kinase Inhibitor as a new Therapy for Ischemic Stroke and other Neurologic Diseases: is there any Hope for a Better Outcome?7,8-DHF Treatment Induces Cyr61 Expression to Suppress Hypoxia Induced ER Stress in HK-2 Cells.Natural Compounds as a Therapeutic Intervention following Traumatic Brain Injury: The Role of Phytochemicals.Therapeutic potential of brain-derived neurotrophic factor (BDNF) and a small molecular mimics of BDNF for traumatic brain injury.The Small-Molecule TrkB Agonist 7, 8-Dihydroxyflavone Decreases Hippocampal Newborn Neuron Death After Traumatic Brain Injury.Antidepressant-like effects and cognitive enhancement of Schisandra chinensis in chronic unpredictable mild stress mice and its related mechanism.Primary Blast-Induced Changes in Akt and GSK3β Phosphorylation in Rat Hippocampus.TrkB-enhancer facilitates functional recovery after traumatic brain injury.Post-Injury Treatment of 7,8-Dihydroxyflavone Promotes Neurogenesis in the Hippocampus of the Adult Mouse.Low-intensity pulsed ultrasound improves behavioral and histological outcomes after experimental traumatic brain injury.Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury.Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage.Brain-derived neurotrophic factor delivered to the brain using poly (lactide-co-glycolide) nanoparticles improves neurological and cognitive outcome in mice with traumatic brain injury.Upregulation of Interferon Regulatory Factor 6 Promotes Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats.Neuroprotective effect of dexmedetomidine in a murine model of traumatic brain injury.
P2860
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P2860
Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling
description
2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@ast
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en-gb
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
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type
label
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@ast
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en-gb
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@nl
prefLabel
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@ast
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en-gb
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@nl
P2093
P2860
P3181
P1433
P1476
Post-injury treatment with 7,8 ...... injury via PI3K/Akt signaling
@en
P2093
Chia-Hua Ke
Chien-Cheng Chen
Chun-Hu Wu
Chun-Yen Lee
Pei-Yi Wang
Szu-Fu Chen
Tai-Ho Hung
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0113397
P407
P577
2014-01-01T00:00:00Z