When the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitoses
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerThe "virgin birth", polyploidy, and the origin of cancerSingle-cell lineage tracking analysis reveals that an established cell line comprises putative cancer stem cells and their heterogeneous progeny.Intratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid stateGeneration of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesisChromosomal instability in mouse embryonic fibroblasts null for the transcriptional co-repressor Ski.Transgenerational cell fate profiling: a method for the graphical presentation of complex cell cycle alterationsThree steps to the immortality of cancer cells: senescence, polyploidy and self-renewal.Usp7 protects genomic stability by regulating Bub3.p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cellsDeletions of 16q in Wilms tumors localize to blastemal-anaplastic cells and are associated with reduced expression of the IRXB renal tubulogenesis gene cluster.Chlamydia induces anchorage independence in 3T3 cells and detrimental cytological defects in an infection model.Illicit survival of cancer cells during polyploidization and depolyploidization.Sources of contradictions in the evaluation of population genetic consequences after the chernobyl disaster.MOS, aneuploidy and the ploidy cycle of cancer cells.Mechanisms of whole chromosome gains in tumors--many answers to a simple question.Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites.Polyploid tumour cells elicit paradiploid progeny through depolyploidizing divisions and regulated autophagic degradation.Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression.Folate deficiency induces mitotic aberrations and chromosomal instability by compromising the spindle assembly checkpoint in cultured human colon cells.Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity.
P2860
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P2860
When the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitoses
description
2008 nî lūn-bûn
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2008 թուականին հրատարակուած գիտական յօդուած
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2008 թվականին հրատարակված գիտական հոդված
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年论文
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When the genome plays dice: ci ...... multipolar cancer cell mitoses
@ast
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en-gb
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@nl
type
label
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@ast
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en-gb
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@nl
altLabel
When the Genome Plays Dice: Ci ...... Multipolar Cancer Cell Mitoses
@en
prefLabel
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@ast
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en-gb
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@nl
P2093
P2860
P50
P3181
P1433
P1476
When the genome plays dice: ci ...... multipolar cancer cell mitoses
@en
P2093
Anders H Rosengren
David Gisselsson
Fredrik Kahl
Ulf Håkanson
Ylva Stewénius
Yuesheng Jin
P2860
P3181
P356
10.1371/JOURNAL.PONE.0001871
P407
P577
2008-01-01T00:00:00Z