about
P688
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiationHolt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene familyMutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndromeTbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron developmentCooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heartUTX and UTY demonstrate histone demethylase-independent function in mouse embryonic developmentThe T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction systemDifferential expression and function of Tbx5 and Tbx20 in cardiac developmentTbx5 and Tbx4 are not sufficient to determine limb-specific morphologies but have common roles in initiating limb outgrowthTbx5-hedgehog molecular networks are essential in the second heart field for atrial septationHistone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesisCardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heartTbx5-dependent rheostatic control of cardiac gene expression and morphogenesisA molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system developmentTbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryoTbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndromeReptilian heart development and the molecular basis of cardiac chamber evolutionDirect reprogramming of fibroblasts into functional cardiomyocytes by defined factors.Tbx5 is required for forelimb bud formation and continued outgrowthUTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental programT-box gene products are required for mesenchymal induction of epithelial branching in the embryonic mouse lungA murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and diseaseCharacterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndromeInteraction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac developmentThe Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation
P921
Q24291385-C4EC8FCA-6F8D-437E-A07C-9F88E51D579EQ24311501-C8775247-93A9-45D9-8882-F53E95669526Q24311600-A6D89BFE-39D4-4922-9CCD-B2CB470340F3Q28246208-4CCF96EA-ED01-4FE3-B9AB-974D3240948BQ28289031-D32B608F-87C5-46FC-AF13-74070370A878Q28484095-9E007D1B-92A4-4EB6-830A-0E3E457AD458Q28507264-E8FF1859-D68C-4E0B-96E7-874F17075C84Q28508533-C405D978-7BEF-4F0B-B91A-EC2BD44EB4FAQ28508863-477F76E3-6122-435B-AA88-5E03F880FBAEQ28509085-194D4424-B801-40FD-BFCF-12FAFE1DBF88Q28509707-1457849F-747D-4BDE-BD53-2BE88235C64EQ28510052-A8CFA9FB-2F86-436B-A04D-99DEF043F426Q28510707-F0D0B476-C955-4360-A854-29EE568F7E69Q28512323-CF045B90-05B6-45DD-8B9B-A0AD23AF1497Q28586325-AA4D6556-F751-4220-BFA4-CCC78EECBCD1Q28587462-1EBA33A9-22B1-451F-BDD6-821ED33FE3D6Q28587652-D444189A-8219-43BD-B1A7-AA3B81DABE18Q28589872-2E55CC1B-B419-4D11-8409-78BFF8F7CA33Q28591196-3CA9E4D6-CE34-458B-8161-821685782A05Q28591296-FB8B20F6-DE9A-4B69-8438-076E548A8534Q28593388-510D853E-1245-4D26-8C51-527B5DBBE404Q28594121-82E97E17-DF15-4223-A1E5-4EC871EEF6EBQ28594224-543A4594-6720-49A4-A929-003A1FE5ED3EQ28594374-121B4958-736E-4FC6-8EEC-153C8619F2DCQ37036085-9018E2DE-29CD-4369-9C2E-B0BB496C3693
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in T-box 5
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
T-box 5
@en
type
label
T-box 5
@en
altLabel
T-box protein 5
@en
T-box transcription factor TBX5
@en
Tbx5
@en
prefLabel
T-box 5
@en
P361
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P680
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P279
P31
P352
P637
XP_006530342
XP_006530343
XP_006530344
XP_006530345
XP_006530346
XP_011246493
P680
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P702
P703
P705
ENSMUSP00000018407
ENSMUSP00000143828
ENSMUSP00000144418